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Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice
Physical exercise improves memory and cognition in physiological aging and Alzheimer’s disease (AD), but the mechanisms remain poorly understood. Here, we test the hypothesis that Aβ oligomer accumulation, neuroinflammation, and glial cell activation may lead to disruption of synaptic transmission i...
Autores principales: | Mu, Lianwei, Xia, Dongdong, Cai, Jiajia, Gu, Boya, Liu, Xiaojie, Friedman, Vladislav, Liu, Qing-Song, Zhao, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604030/ https://www.ncbi.nlm.nih.gov/pubmed/36293516 http://dx.doi.org/10.3390/ijms232012655 |
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