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AMPK Amplifies IL2–STAT5 Signaling to Maintain Stability of Regulatory T Cells in Aged Mice

AMP-activated protein kinase (AMPK), an important regulator of the aging process, is expressed in various immune cells. However, its role in regulatory T cell (Treg) stability during aging is poorly understood. Here, we addressed the role of AMPK in Treg function and stability during aging by genera...

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Detalles Bibliográficos
Autores principales: Pokhrel, Ram Hari, Kang, Ben, Timilshina, Maheshwor, Chang, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604214/
https://www.ncbi.nlm.nih.gov/pubmed/36293240
http://dx.doi.org/10.3390/ijms232012384