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Mitochondria-Targeting Polymer Micelles in Stepwise Response Releasing Gemcitabine and Destroying the Mitochondria and Nucleus for Combined Antitumor Chemotherapy
Mitochondrial DNA and nuclear DNA are essential genetic material which play an important role in maintaining normal metabolism, survival, and proliferation of cells. Constructing a mitochondria-targeting stimuli-responsive nano-drug delivery system releasing chemotherapeutic agents in a stepwise res...
Autores principales: | Zhang, Shanming, Zheng, Fen, Liu, Kaige, Liu, Shengke, Xiao, Tonghu, Zhu, Yabin, Xu, Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604266/ https://www.ncbi.nlm.nih.gov/pubmed/36293476 http://dx.doi.org/10.3390/ijms232012624 |
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