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mTOR Contributes to the Proteome Diversity through Transcriptome-Wide Alternative Splicing

The mammalian target of rapamycin (mTOR) pathway is crucial in energy metabolism and cell proliferation. Previously, we reported transcriptome-wide 3′-untranslated region (UTR) shortening by alternative polyadenylation upon mTOR activation and its impact on the proteome. Here, we further interrogate...

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Detalles Bibliográficos
Autores principales: Cheng, Sze, Fahmi, Naima Ahmed, Park, Meeyeon, Sun, Jiao, Thao, Kaitlyn, Yeh, Hsin-Sung, Zhang, Wei, Yong, Jeongsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604279/
https://www.ncbi.nlm.nih.gov/pubmed/36293270
http://dx.doi.org/10.3390/ijms232012416