A Novel Antibody-Drug Conjugate Targeting Nectin-2 Suppresses Ovarian Cancer Progression in Mouse Xenograft Models

Ovarian cancer is the fifth leading cause of cancer, followed by front line is mostly platinum agents and PARP inhibitors, and very limited option in later lines. Therefore, there is a need for alternative therapeutic options. Nectin-2, which is overexpressed in ovarian cancer, is a known immune che...

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Detalles Bibliográficos
Autores principales: Sim, Yun Hee, Um, Yun Jung, Park, Jeong-Yang, Seo, Min-Duk, Park, Sang Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604294/
https://www.ncbi.nlm.nih.gov/pubmed/36293219
http://dx.doi.org/10.3390/ijms232012358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604294/
https://www.ncbi.nlm.nih.gov/pubmed/36293219
http://dx.doi.org/10.3390/ijms232012358

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