Cargando…

Plasma Extracellular Vesicles Play a Role in Immune System Modulation in Minimal Hepatic Encephalopathy

Minimal hepatic encephalopathy (MHE) is associated with changes in the immune system including an increased pro-inflammatory environment and altered differentiation of CD4+ T lymphocytes. The mechanisms remain unknown. Changes in extracellular vesicle (EV) cargo including proteins and miRNAs could p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallego, Juan José, Fiorillo, Alessandra, Casanova-Ferrer, Franc, Urios, Amparo, Ballester, María-Pilar, Durbán, Lucia, Megías, Javier, Rubio, Teresa, Cabrera-Pastor, Andrea, Escudero-García, Desamparados, Felipo, Vicente, Montoliu, Carmina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604313/ https://www.ncbi.nlm.nih.gov/pubmed/36293192 http://dx.doi.org/10.3390/ijms232012335

Ejemplares similares

Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy
por: Ballester, María-Pilar, et al.
Publicado: (2022)

Minimal hepatic encephalopathy is associated to alterations in eye movements
por: Casanova-Ferrer, Franc, et al.
Publicado: (2022)

Neurofilament Light Chain Protein in Plasma and Extracellular Vesicles Is Associated with Minimal Hepatic Encephalopathy and Responses to Rifaximin Treatment in Cirrhotic Patients
por: Fiorillo, Alessandra, et al.
Publicado: (2023)

Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease
por: Fiorillo, Alessandra, et al.
Publicado: (2023)

Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function
por: Rega, Dalia, et al.
Publicado: (2021)

Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients
por: Rubio, Teresa, et al.
Publicado: (2021)

Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy
por: Mangas-Losada, Alba, et al.
Publicado: (2019)

A New Score Unveils a High Prevalence of Mild Cognitive Impairment in Patients with Nonalcoholic Fatty Liver Disease
por: Giménez-Garzó, Carla, et al.
Publicado: (2021)

Minimal hepatic encephalopathy is associated with expansion and activation of CD(4+)CD28(−), Th22 and Tfh and B lymphocytes
por: Mangas-Losada, Alba, et al.
Publicado: (2017)

Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy
por: San Martín-Valenzuela, Constanza, et al.
Publicado: (2020)

Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus
por: García-García, Raquel, et al.
Publicado: (2018)

Reduced resting state connectivity and gray matter volume correlate with cognitive impairment in minimal hepatic encephalopathy
por: García-García, Raquel, et al.
Publicado: (2017)

Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction
por: Urios, Amparo, et al.
Publicado: (2019)

The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons
por: Balzano, Tiziano, et al.
Publicado: (2018)

Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms
por: Hernandez-Rabaza, Vicente, et al.
Publicado: (2015)

The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients
por: Tenorio-Laranga, Jofre, et al.
Publicado: (2015)

The PHES battery does not detect all cirrhotic patients with early neurological deficits, which are different in different patients
por: Giménez-Garzó, Carla, et al.
Publicado: (2017)

Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats
por: Izquierdo-Altarejos, Paula, et al.
Publicado: (2020)

The Erythrocytic Hypothesis of Brain Energy Crisis in Sporadic Alzheimer Disease: Possible Consequences and Supporting Evidence
por: Kosenko, Elena, et al.
Publicado: (2020)

GR3027 antagonizes GABA(A) receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy
por: Johansson, Maja, et al.
Publicado: (2015)

Automatic Video-Oculography System for Detection of Minimal Hepatic Encephalopathy Using Machine Learning Tools
por: Calvo Córdoba, Alberto, et al.
Publicado: (2023)

Metabolism of cyclic GMP in non-alcoholic fatty liver disease in morbid obesity
por: Urios, Amparo, et al.
Publicado: (2011)

Is NMDA-Receptor-Mediated Oxidative Stress in Mitochondria of Peripheral Tissues the Essential Factor in the Pathogenesis of Hepatic Encephalopathy?
por: Kosenko, Elena, et al.
Publicado: (2022)

Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications
por: Rodrigo, Regina, et al.
Publicado: (2006)

A Look into Liver Mitochondrial Dysfunction as a Hallmark in Progression of Brain Energy Crisis and Development of Neurologic Symptoms in Hepatic Encephalopathy
por: Kosenko, Elena, et al.
Publicado: (2020)

Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy
por: Dadsetan, Sherry, et al.
Publicado: (2016)

Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy
por: Dadsetan, Sherry, et al.
Publicado: (2016)

Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-κB pathway
por: Balzano, Tiziano, et al.
Publicado: (2020)

Extracellular Cyclic GMP Modulates Membrane Expression of The GluA1 and GluA2 Subunits of AMPA Receptor in Cerebellum: Molecular Mechanisms Involved
por: Cabrera-Pastor, Andrea, et al.
Publicado: (2017)

Movements of a juvenile Crowned Eagle (Harpyhaliaetus coronatus) tracked by satellite telemetry in central Argentina
por: Urios, Vicente, et al.
Publicado: (2014)

Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms
por: Taoro-Gonzalez, Lucas, et al.
Publicado: (2018)

Extracellular cGMP Modulates Learning Biphasically by Modulating Glycine Receptors, CaMKII and Glutamate-Nitric Oxide-cGMP Pathway
por: Cabrera-Pastor, Andrea, et al.
Publicado: (2016)

Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase, alterations in hyperammonemia
por: Monfort, Pilar, et al.
Publicado: (2005)

Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway
por: Arenas, Yaiza M., et al.
Publicado: (2020)

Long-Term Analyses of the Rate of Perceived Exertion as an Indicator of Intensity in Women’s Basketball during a Relegation Play-off
por: Batalla-Gavalda, Abraham, et al.
Publicado: (2022)

Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane
por: Hernández-Rabaza, Vicente, et al.
Publicado: (2016)

Duration of American Football Play and Chronic Traumatic Encephalopathy
por: Mez, Jesse, et al.
Publicado: (2019)

Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia
por: Hernandez-Rabaza, Vicente, et al.
Publicado: (2016)

Matched Paired Primary and Recurrent Meningiomas Points to Cell-Death Program Contributions to Genomic and Epigenomic Instability along Tumor Progression
por: San-Miguel, Teresa, et al.
Publicado: (2022)

Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats
por: Izquierdo-Altarejos, Paula, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6v9v30jlvrmj88vk16vm9o6if7