Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium

Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and...

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Detalles Bibliográficos
Autores principales: Ceccarelli, Fulvia, Govoni, Marcello, Piga, Matteo, Cassone, Giulia, Cantatore, Francesco Paolo, Olivieri, Giulio, Cauli, Alberto, Favalli, Ennio Giulio, Atzeni, Fabiola, Gremese, Elisa, Iannone, Florenzo, Caporali, Roberto, Sebastiani, Marco, Ferraccioli, Gian Franco, Lapadula, Giovanni, Conti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604412/
https://www.ncbi.nlm.nih.gov/pubmed/36294337
http://dx.doi.org/10.3390/jcm11206016
Descripción
Sumario:Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and MRI findings. Identifying the pathogenetic mechanisms underlying musculoskeletal manifestations’ development is crucial to develop therapeutic strategies to suppress synovial inflammation, prevent erosions and deformities, and improve SLE patients’ quality of life. Hence, here we discuss the main pathogenetic mechanisms and therapeutic approaches of musculoskeletal manifestations of SLE from the 2022 International GISEA/OEG Symposium.

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