Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium

Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and...

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Autores principales: Ceccarelli, Fulvia, Govoni, Marcello, Piga, Matteo, Cassone, Giulia, Cantatore, Francesco Paolo, Olivieri, Giulio, Cauli, Alberto, Favalli, Ennio Giulio, Atzeni, Fabiola, Gremese, Elisa, Iannone, Florenzo, Caporali, Roberto, Sebastiani, Marco, Ferraccioli, Gian Franco, Lapadula, Giovanni, Conti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604412/
https://www.ncbi.nlm.nih.gov/pubmed/36294337
http://dx.doi.org/10.3390/jcm11206016
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author Ceccarelli, Fulvia
Govoni, Marcello
Piga, Matteo
Cassone, Giulia
Cantatore, Francesco Paolo
Olivieri, Giulio
Cauli, Alberto
Favalli, Ennio Giulio
Atzeni, Fabiola
Gremese, Elisa
Iannone, Florenzo
Caporali, Roberto
Sebastiani, Marco
Ferraccioli, Gian Franco
Lapadula, Giovanni
Conti, Fabrizio
author_facet Ceccarelli, Fulvia
Govoni, Marcello
Piga, Matteo
Cassone, Giulia
Cantatore, Francesco Paolo
Olivieri, Giulio
Cauli, Alberto
Favalli, Ennio Giulio
Atzeni, Fabiola
Gremese, Elisa
Iannone, Florenzo
Caporali, Roberto
Sebastiani, Marco
Ferraccioli, Gian Franco
Lapadula, Giovanni
Conti, Fabrizio
author_sort Ceccarelli, Fulvia
collection PubMed
description Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and MRI findings. Identifying the pathogenetic mechanisms underlying musculoskeletal manifestations’ development is crucial to develop therapeutic strategies to suppress synovial inflammation, prevent erosions and deformities, and improve SLE patients’ quality of life. Hence, here we discuss the main pathogenetic mechanisms and therapeutic approaches of musculoskeletal manifestations of SLE from the 2022 International GISEA/OEG Symposium.
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spelling pubmed-96044122022-10-27 Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium Ceccarelli, Fulvia Govoni, Marcello Piga, Matteo Cassone, Giulia Cantatore, Francesco Paolo Olivieri, Giulio Cauli, Alberto Favalli, Ennio Giulio Atzeni, Fabiola Gremese, Elisa Iannone, Florenzo Caporali, Roberto Sebastiani, Marco Ferraccioli, Gian Franco Lapadula, Giovanni Conti, Fabrizio J Clin Med Review Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and MRI findings. Identifying the pathogenetic mechanisms underlying musculoskeletal manifestations’ development is crucial to develop therapeutic strategies to suppress synovial inflammation, prevent erosions and deformities, and improve SLE patients’ quality of life. Hence, here we discuss the main pathogenetic mechanisms and therapeutic approaches of musculoskeletal manifestations of SLE from the 2022 International GISEA/OEG Symposium. MDPI 2022-10-12 /pmc/articles/PMC9604412/ /pubmed/36294337 http://dx.doi.org/10.3390/jcm11206016 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ceccarelli, Fulvia
Govoni, Marcello
Piga, Matteo
Cassone, Giulia
Cantatore, Francesco Paolo
Olivieri, Giulio
Cauli, Alberto
Favalli, Ennio Giulio
Atzeni, Fabiola
Gremese, Elisa
Iannone, Florenzo
Caporali, Roberto
Sebastiani, Marco
Ferraccioli, Gian Franco
Lapadula, Giovanni
Conti, Fabrizio
Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title_full Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title_fullStr Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title_full_unstemmed Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title_short Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium
title_sort arthritis in systemic lupus erythematosus: from 2022 international gisea/oeg symposium
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604412/
https://www.ncbi.nlm.nih.gov/pubmed/36294337
http://dx.doi.org/10.3390/jcm11206016
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