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Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery
Background This study compared the clinical outcomes of transcatheter (TAVR) and surgical (SAVR) aortic valve replacements, focusing on postoperative valvular performance assessed by echocardiography. Method and Results A total of 425 patients who underwent TAVR (230 patients) or SAVR (195 patients)...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604414/ https://www.ncbi.nlm.nih.gov/pubmed/36286307 http://dx.doi.org/10.3390/jcdd9100355 |
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author | Saito, Shunsuke Sairenchi, Toshimi Hirota, Shotaro Niitsuma, Ken Yokoyama, Shohei Kanno, Yasuyuki Kanazawa, Yuta Tezuka, Masahiro Takei, Yusuke Tsuchiya, Go Konishi, Taisuke Shibasaki, Ikuko Ogata, Koji Monta, Osamu Tsutsumi, Yasushi Fukuda, Hirotsugu |
author_facet | Saito, Shunsuke Sairenchi, Toshimi Hirota, Shotaro Niitsuma, Ken Yokoyama, Shohei Kanno, Yasuyuki Kanazawa, Yuta Tezuka, Masahiro Takei, Yusuke Tsuchiya, Go Konishi, Taisuke Shibasaki, Ikuko Ogata, Koji Monta, Osamu Tsutsumi, Yasushi Fukuda, Hirotsugu |
author_sort | Saito, Shunsuke |
collection | PubMed |
description | Background This study compared the clinical outcomes of transcatheter (TAVR) and surgical (SAVR) aortic valve replacements, focusing on postoperative valvular performance assessed by echocardiography. Method and Results A total of 425 patients who underwent TAVR (230 patients) or SAVR (195 patients) were included. Postoperative effective orifice area index (EOAI) was higher in the TAVR group (1.27 ± 0.35 cm(2)/m(2)) than in the SAVR group (1.06 ± 0.27 cm(2)/m(2), p < 0.001), and patient–prosthesis mismatch (PPM) was more frequent in the SAVR group (22.6%) than in the TAVR group (8.7%, p < 0.001). Mild or greater paravalvular leakage (PVL) was more frequent in the TAVR group (21.3%) than in the SAVR group (0%, p < 0.001). Moreover, there was no difference in freedom from all-cause death, stroke, or rehospitalization between the groups. Patients with moderate or greater PPM (EOAI < 0.85 cm(2)/m(2)) had lower freedom from composite events than those without this PPM criterion (p = 0.008). Patients with mild or greater PVL also had lower freedom from composite events than those without this PVL criterion (p = 0.017). Conclusions Postoperative valvular performance of TAVR was superior to that of SAVR in terms of EOAI. This merit was counterbalanced by the significantly lower rates of PVL in patients who underwent SAVR. The overall clinical outcomes were similar between the study groups. |
format | Online Article Text |
id | pubmed-9604414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96044142022-10-27 Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery Saito, Shunsuke Sairenchi, Toshimi Hirota, Shotaro Niitsuma, Ken Yokoyama, Shohei Kanno, Yasuyuki Kanazawa, Yuta Tezuka, Masahiro Takei, Yusuke Tsuchiya, Go Konishi, Taisuke Shibasaki, Ikuko Ogata, Koji Monta, Osamu Tsutsumi, Yasushi Fukuda, Hirotsugu J Cardiovasc Dev Dis Article Background This study compared the clinical outcomes of transcatheter (TAVR) and surgical (SAVR) aortic valve replacements, focusing on postoperative valvular performance assessed by echocardiography. Method and Results A total of 425 patients who underwent TAVR (230 patients) or SAVR (195 patients) were included. Postoperative effective orifice area index (EOAI) was higher in the TAVR group (1.27 ± 0.35 cm(2)/m(2)) than in the SAVR group (1.06 ± 0.27 cm(2)/m(2), p < 0.001), and patient–prosthesis mismatch (PPM) was more frequent in the SAVR group (22.6%) than in the TAVR group (8.7%, p < 0.001). Mild or greater paravalvular leakage (PVL) was more frequent in the TAVR group (21.3%) than in the SAVR group (0%, p < 0.001). Moreover, there was no difference in freedom from all-cause death, stroke, or rehospitalization between the groups. Patients with moderate or greater PPM (EOAI < 0.85 cm(2)/m(2)) had lower freedom from composite events than those without this PPM criterion (p = 0.008). Patients with mild or greater PVL also had lower freedom from composite events than those without this PVL criterion (p = 0.017). Conclusions Postoperative valvular performance of TAVR was superior to that of SAVR in terms of EOAI. This merit was counterbalanced by the significantly lower rates of PVL in patients who underwent SAVR. The overall clinical outcomes were similar between the study groups. MDPI 2022-10-16 /pmc/articles/PMC9604414/ /pubmed/36286307 http://dx.doi.org/10.3390/jcdd9100355 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saito, Shunsuke Sairenchi, Toshimi Hirota, Shotaro Niitsuma, Ken Yokoyama, Shohei Kanno, Yasuyuki Kanazawa, Yuta Tezuka, Masahiro Takei, Yusuke Tsuchiya, Go Konishi, Taisuke Shibasaki, Ikuko Ogata, Koji Monta, Osamu Tsutsumi, Yasushi Fukuda, Hirotsugu Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title | Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title_full | Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title_fullStr | Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title_full_unstemmed | Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title_short | Prosthetic Valve Function after Aortic Valve Replacement for Severe Aortic Stenosis by Transcatheter Procedure versus Surgery |
title_sort | prosthetic valve function after aortic valve replacement for severe aortic stenosis by transcatheter procedure versus surgery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604414/ https://www.ncbi.nlm.nih.gov/pubmed/36286307 http://dx.doi.org/10.3390/jcdd9100355 |
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