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Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease

Life-space activities are a measure of daily activity level. Here, we examined the association between life-space activities and prognosis in 129 cardiovascular diseases (CVD) patients 65 years of age or older (average age, 79.2 ± 7.6 years; mean left ventricular ejection fraction, 56.7 ± 13.2%) who...

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Autores principales: Hashimoto, Kakeru, Hirashiki, Akihiro, Oya, Koharu, Sugioka, Junpei, Tanioku, Shunya, Sato, Kenji, Ueda, Ikue, Itoh, Naoki, Kokubo, Manabu, Shimizu, Atsuya, Kagaya, Hitoshi, Kondo, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604436/
https://www.ncbi.nlm.nih.gov/pubmed/36286275
http://dx.doi.org/10.3390/jcdd9100323
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author Hashimoto, Kakeru
Hirashiki, Akihiro
Oya, Koharu
Sugioka, Junpei
Tanioku, Shunya
Sato, Kenji
Ueda, Ikue
Itoh, Naoki
Kokubo, Manabu
Shimizu, Atsuya
Kagaya, Hitoshi
Kondo, Izumi
author_facet Hashimoto, Kakeru
Hirashiki, Akihiro
Oya, Koharu
Sugioka, Junpei
Tanioku, Shunya
Sato, Kenji
Ueda, Ikue
Itoh, Naoki
Kokubo, Manabu
Shimizu, Atsuya
Kagaya, Hitoshi
Kondo, Izumi
author_sort Hashimoto, Kakeru
collection PubMed
description Life-space activities are a measure of daily activity level. Here, we examined the association between life-space activities and prognosis in 129 cardiovascular diseases (CVD) patients 65 years of age or older (average age, 79.2 ± 7.6 years; mean left ventricular ejection fraction, 56.7 ± 13.2%) who had been admitted to our hospital for worsening CVD. Subjects were followed, and the primary endpoints were cardiovascular hospitalization and cardiovascular death. Receiver operating characteristic analysis produced a cutoff value for life-space assessment (LSA) score for increased risk of cardiovascular hospitalization for two years of 53.0 points (sensitivity, 55.9%; specificity, 82.1%). Kaplan–Meier analysis using this cutoff value revealed that the rates of cardiovascular hospitalization and cardiovascular death were significantly higher in subjects with an LSA score below the cutoff than in those with a score above the cutoff (both p < 0.001). Cox proportional analysis revealed that low LSA score was independently associated with cardiovascular hospitalization (HR, 2.540; 95% CI, 1.135–5.680; p = 0.023) and cardiovascular death (HR, 15.223; 95% CI, 1.689–137.180; p = 0.015), even after adjusting for age, sex, left ventricular ejection fraction, and log-transformed brain natriuretic peptide level. Thus, life-space activities are associated with prognosis in older adults with CVD.
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spelling pubmed-96044362022-10-27 Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease Hashimoto, Kakeru Hirashiki, Akihiro Oya, Koharu Sugioka, Junpei Tanioku, Shunya Sato, Kenji Ueda, Ikue Itoh, Naoki Kokubo, Manabu Shimizu, Atsuya Kagaya, Hitoshi Kondo, Izumi J Cardiovasc Dev Dis Article Life-space activities are a measure of daily activity level. Here, we examined the association between life-space activities and prognosis in 129 cardiovascular diseases (CVD) patients 65 years of age or older (average age, 79.2 ± 7.6 years; mean left ventricular ejection fraction, 56.7 ± 13.2%) who had been admitted to our hospital for worsening CVD. Subjects were followed, and the primary endpoints were cardiovascular hospitalization and cardiovascular death. Receiver operating characteristic analysis produced a cutoff value for life-space assessment (LSA) score for increased risk of cardiovascular hospitalization for two years of 53.0 points (sensitivity, 55.9%; specificity, 82.1%). Kaplan–Meier analysis using this cutoff value revealed that the rates of cardiovascular hospitalization and cardiovascular death were significantly higher in subjects with an LSA score below the cutoff than in those with a score above the cutoff (both p < 0.001). Cox proportional analysis revealed that low LSA score was independently associated with cardiovascular hospitalization (HR, 2.540; 95% CI, 1.135–5.680; p = 0.023) and cardiovascular death (HR, 15.223; 95% CI, 1.689–137.180; p = 0.015), even after adjusting for age, sex, left ventricular ejection fraction, and log-transformed brain natriuretic peptide level. Thus, life-space activities are associated with prognosis in older adults with CVD. MDPI 2022-09-24 /pmc/articles/PMC9604436/ /pubmed/36286275 http://dx.doi.org/10.3390/jcdd9100323 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hashimoto, Kakeru
Hirashiki, Akihiro
Oya, Koharu
Sugioka, Junpei
Tanioku, Shunya
Sato, Kenji
Ueda, Ikue
Itoh, Naoki
Kokubo, Manabu
Shimizu, Atsuya
Kagaya, Hitoshi
Kondo, Izumi
Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title_full Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title_fullStr Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title_full_unstemmed Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title_short Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease
title_sort life-space activities are associated with the prognosis of older adults with cardiovascular disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604436/
https://www.ncbi.nlm.nih.gov/pubmed/36286275
http://dx.doi.org/10.3390/jcdd9100323
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