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Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair

Background: The aim of this study was to evaluate the aortic diameter and volume during the first year after a type A repair to predict the long-term prognosis of a residual aortic dissection (RAD). Methods: All patients treated in our center for an acute type A dissection with a RAD and follow-up &...

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Autores principales: Gaudry, Marine, Guivier-Curien, Carine, Blanchard, Arnaud, Porto, Alizée, Bal, Laurence, Omnes, Virgile, De Masi, Mariangela, Lu, Charlotte, Jacquier, Alexis, Piquet, Philippe, Deplano, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604488/
https://www.ncbi.nlm.nih.gov/pubmed/36286301
http://dx.doi.org/10.3390/jcdd9100349
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author Gaudry, Marine
Guivier-Curien, Carine
Blanchard, Arnaud
Porto, Alizée
Bal, Laurence
Omnes, Virgile
De Masi, Mariangela
Lu, Charlotte
Jacquier, Alexis
Piquet, Philippe
Deplano, Valerie
author_facet Gaudry, Marine
Guivier-Curien, Carine
Blanchard, Arnaud
Porto, Alizée
Bal, Laurence
Omnes, Virgile
De Masi, Mariangela
Lu, Charlotte
Jacquier, Alexis
Piquet, Philippe
Deplano, Valerie
author_sort Gaudry, Marine
collection PubMed
description Background: The aim of this study was to evaluate the aortic diameter and volume during the first year after a type A repair to predict the long-term prognosis of a residual aortic dissection (RAD). Methods: All patients treated in our center for an acute type A dissection with a RAD and follow-up > 3 years were included. We defined two groups: group 1 with dissection-related events (defined as an aneurysmal evolution, distal reintervention, or aortic-related death) and group 2 without dissection-related events. The aortic diameters and volume analysis were evaluated on three postoperative CT scans: pre-discharge (T1), 3–6 months (T2) and 1 year (T3). Results: Between 2009 and 2016, 54 patients were included. Following a mean follow-up of 75.4 months (SD 31.5), the rate of dissection-related events was 62.9% (34/54). The total aortic diameters of the descending thoracic aorta were greater in group 1 at T1, T2 and T3, with greater diameters in the FL (p < 0.01). The aortic diameter evolution at 3 months was not predictive of long-term dissection-related events. The total thoracic aortic volume was significantly greater in group 1 at T1 (p < 0.01), T2 (p < 0.01), and T3 (p < 0.01). At 3 months, the increase in the FL volume was significantly greater in group 1 (p < 0.01) and was predictive for long-term dissection-related events. Conclusion: This study shows that an initial CT scan volume analysis coupled with another at 3 months is predictive for the long-term evolution in a RAD. Based on this finding, more aggressive treatment could be given at an earlier stage.
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spelling pubmed-96044882022-10-27 Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair Gaudry, Marine Guivier-Curien, Carine Blanchard, Arnaud Porto, Alizée Bal, Laurence Omnes, Virgile De Masi, Mariangela Lu, Charlotte Jacquier, Alexis Piquet, Philippe Deplano, Valerie J Cardiovasc Dev Dis Article Background: The aim of this study was to evaluate the aortic diameter and volume during the first year after a type A repair to predict the long-term prognosis of a residual aortic dissection (RAD). Methods: All patients treated in our center for an acute type A dissection with a RAD and follow-up > 3 years were included. We defined two groups: group 1 with dissection-related events (defined as an aneurysmal evolution, distal reintervention, or aortic-related death) and group 2 without dissection-related events. The aortic diameters and volume analysis were evaluated on three postoperative CT scans: pre-discharge (T1), 3–6 months (T2) and 1 year (T3). Results: Between 2009 and 2016, 54 patients were included. Following a mean follow-up of 75.4 months (SD 31.5), the rate of dissection-related events was 62.9% (34/54). The total aortic diameters of the descending thoracic aorta were greater in group 1 at T1, T2 and T3, with greater diameters in the FL (p < 0.01). The aortic diameter evolution at 3 months was not predictive of long-term dissection-related events. The total thoracic aortic volume was significantly greater in group 1 at T1 (p < 0.01), T2 (p < 0.01), and T3 (p < 0.01). At 3 months, the increase in the FL volume was significantly greater in group 1 (p < 0.01) and was predictive for long-term dissection-related events. Conclusion: This study shows that an initial CT scan volume analysis coupled with another at 3 months is predictive for the long-term evolution in a RAD. Based on this finding, more aggressive treatment could be given at an earlier stage. MDPI 2022-10-12 /pmc/articles/PMC9604488/ /pubmed/36286301 http://dx.doi.org/10.3390/jcdd9100349 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gaudry, Marine
Guivier-Curien, Carine
Blanchard, Arnaud
Porto, Alizée
Bal, Laurence
Omnes, Virgile
De Masi, Mariangela
Lu, Charlotte
Jacquier, Alexis
Piquet, Philippe
Deplano, Valerie
Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title_full Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title_fullStr Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title_full_unstemmed Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title_short Volume Analysis to Predict the Long-Term Evolution of Residual Aortic Dissection after Type A Repair
title_sort volume analysis to predict the long-term evolution of residual aortic dissection after type a repair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604488/
https://www.ncbi.nlm.nih.gov/pubmed/36286301
http://dx.doi.org/10.3390/jcdd9100349
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