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Choroidal Melanocytic Hamartoma

We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor(®) (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patien...

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Autores principales: Venkatesh, Ramesh, Agrawal, Sameeksha, Reddy, Nikitha Gurram, Mangla, Rubble, Yadav, Naresh Kumar, Chhablani, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604492/
https://www.ncbi.nlm.nih.gov/pubmed/36294307
http://dx.doi.org/10.3390/jcm11205983
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author Venkatesh, Ramesh
Agrawal, Sameeksha
Reddy, Nikitha Gurram
Mangla, Rubble
Yadav, Naresh Kumar
Chhablani, Jay
author_facet Venkatesh, Ramesh
Agrawal, Sameeksha
Reddy, Nikitha Gurram
Mangla, Rubble
Yadav, Naresh Kumar
Chhablani, Jay
author_sort Venkatesh, Ramesh
collection PubMed
description We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor(®) (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patients who had distinct, orange-colored lesions on MCI. Retinal imaging was conducted using conventional color fundus photography and OCT. On the color fundus images and the blue and green reflectance channels of MCI, each of the lesions was difficult to distinguish. On the infrared channel, the lesion was identified as bright white in color and bright orange on the multicolor image. The lesion was identified on OCT as a flat, homogeneous hyperreflective lesion involving the choroid, with an intact overlying retinal pigment epithelium and retinal layers. A comparison of the clinical and imaging features with other known entities led to the conclusion that the lesion was a distinct clinical entity. The presence of melanin in the lesion was confirmed based on the retinal imaging findings and the light absorption properties of melanin. As a result, the lesion was named as ‘choroidal melanocytic hamartoma’. A longer follow-up is required to confirm the benign nature of this clinical entity.
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spelling pubmed-96044922022-10-27 Choroidal Melanocytic Hamartoma Venkatesh, Ramesh Agrawal, Sameeksha Reddy, Nikitha Gurram Mangla, Rubble Yadav, Naresh Kumar Chhablani, Jay J Clin Med Article We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor(®) (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patients who had distinct, orange-colored lesions on MCI. Retinal imaging was conducted using conventional color fundus photography and OCT. On the color fundus images and the blue and green reflectance channels of MCI, each of the lesions was difficult to distinguish. On the infrared channel, the lesion was identified as bright white in color and bright orange on the multicolor image. The lesion was identified on OCT as a flat, homogeneous hyperreflective lesion involving the choroid, with an intact overlying retinal pigment epithelium and retinal layers. A comparison of the clinical and imaging features with other known entities led to the conclusion that the lesion was a distinct clinical entity. The presence of melanin in the lesion was confirmed based on the retinal imaging findings and the light absorption properties of melanin. As a result, the lesion was named as ‘choroidal melanocytic hamartoma’. A longer follow-up is required to confirm the benign nature of this clinical entity. MDPI 2022-10-11 /pmc/articles/PMC9604492/ /pubmed/36294307 http://dx.doi.org/10.3390/jcm11205983 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Venkatesh, Ramesh
Agrawal, Sameeksha
Reddy, Nikitha Gurram
Mangla, Rubble
Yadav, Naresh Kumar
Chhablani, Jay
Choroidal Melanocytic Hamartoma
title Choroidal Melanocytic Hamartoma
title_full Choroidal Melanocytic Hamartoma
title_fullStr Choroidal Melanocytic Hamartoma
title_full_unstemmed Choroidal Melanocytic Hamartoma
title_short Choroidal Melanocytic Hamartoma
title_sort choroidal melanocytic hamartoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604492/
https://www.ncbi.nlm.nih.gov/pubmed/36294307
http://dx.doi.org/10.3390/jcm11205983
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