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Cytomegalovirus US28 regulates cellular EphA2 to maintain viral latency

Cytomegalovirus (CMV) reactivation from latency following immune dysregulation remains a serious risk for patients, often causing substantial morbidity and mortality. Here, we demonstrate the CMV-encoded G protein–coupled receptor, US28, in coordination with cellular Ephrin receptor A2, attenuates m...

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Detalles Bibliográficos
Autores principales: Wass, Amanda B., Krishna, Benjamin A., Herring, Laura E., Gilbert, Thomas S. K., Nukui, Masatoshi, Groves, Ian J., Dooley, Abigail L., Kulp, Katherine H., Matthews, Stephen M., Rotroff, Daniel M., Graves, Lee M., O’Connor, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604534/
https://www.ncbi.nlm.nih.gov/pubmed/36288299
http://dx.doi.org/10.1126/sciadv.add1168

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