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Cladribine Reduces Trans-Endothelial Migration of Memory T Cells across an In Vitro Blood–Brain Barrier

Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS) induced by immune dysregulation. Cladribine has been championed for its clinical efficacy with relatively minor side effects in treating MS. Although it is proposed that cladribine exerts an anti-migrator...

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Detalles Bibliográficos
Autores principales: Ford, Rachel K., Juillard, Pierre, Hawke, Simon, Grau, Georges E., Marsh-Wakefield, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604596/
https://www.ncbi.nlm.nih.gov/pubmed/36294327
http://dx.doi.org/10.3390/jcm11206006