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Bariatric Surgery Outcomes in Patients with Kidney Transplantation

Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful ther...

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Autores principales: Pané, Adriana, Molina-Andujar, Alicia, Olbeyra, Romina, Romano-Andrioni, Bárbara, Boswell, Laura, Montagud-Marrahi, Enrique, Jiménez, Amanda, Ibarzabal, Ainitze, Viaplana, Judith, Ventura-Aguiar, Pedro, Amor, Antonio J., Vidal, Josep, Flores, Lilliam, de Hollanda, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604744/
https://www.ncbi.nlm.nih.gov/pubmed/36294351
http://dx.doi.org/10.3390/jcm11206030
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author Pané, Adriana
Molina-Andujar, Alicia
Olbeyra, Romina
Romano-Andrioni, Bárbara
Boswell, Laura
Montagud-Marrahi, Enrique
Jiménez, Amanda
Ibarzabal, Ainitze
Viaplana, Judith
Ventura-Aguiar, Pedro
Amor, Antonio J.
Vidal, Josep
Flores, Lilliam
de Hollanda, Ana
author_facet Pané, Adriana
Molina-Andujar, Alicia
Olbeyra, Romina
Romano-Andrioni, Bárbara
Boswell, Laura
Montagud-Marrahi, Enrique
Jiménez, Amanda
Ibarzabal, Ainitze
Viaplana, Judith
Ventura-Aguiar, Pedro
Amor, Antonio J.
Vidal, Josep
Flores, Lilliam
de Hollanda, Ana
author_sort Pané, Adriana
collection PubMed
description Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful therapeutic tool either before or after KTx. Since evidence regarding the best approach is still scarce, we aimed to describe renal and metabolic outcomes in a single centre with more than 15-year experience in both surgeries. Methods: A retrospective study including patients who had received a KTx either before or after BS. Usual metabolic and renal outcomes, but also new variables (as renal graft dysfunction) were collected for a minimum follow-up of 1-year post-BS. Results: A total of 11 patients were included: n = 6 (BS-post-KTx) and n = 5 (BS-pre-KTx). One patient was assessed in both groups. No differences in the main outcomes were identified, but BS-post-KTx group tended to gain more weight during the follow-up. The incidence of renal graft dysfunction was comparable (4/6 for BS-post-KTx, 3/5 for BS-pre-KTx) between groups. Conclusions: BS in patients with KTx appears to be safe and effective attending to metabolic and renal outcomes. These results seem irrespective of the time course, except for weight regain, which appears to be a common pattern in the BS-post-KTx group.
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spelling pubmed-96047442022-10-27 Bariatric Surgery Outcomes in Patients with Kidney Transplantation Pané, Adriana Molina-Andujar, Alicia Olbeyra, Romina Romano-Andrioni, Bárbara Boswell, Laura Montagud-Marrahi, Enrique Jiménez, Amanda Ibarzabal, Ainitze Viaplana, Judith Ventura-Aguiar, Pedro Amor, Antonio J. Vidal, Josep Flores, Lilliam de Hollanda, Ana J Clin Med Article Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful therapeutic tool either before or after KTx. Since evidence regarding the best approach is still scarce, we aimed to describe renal and metabolic outcomes in a single centre with more than 15-year experience in both surgeries. Methods: A retrospective study including patients who had received a KTx either before or after BS. Usual metabolic and renal outcomes, but also new variables (as renal graft dysfunction) were collected for a minimum follow-up of 1-year post-BS. Results: A total of 11 patients were included: n = 6 (BS-post-KTx) and n = 5 (BS-pre-KTx). One patient was assessed in both groups. No differences in the main outcomes were identified, but BS-post-KTx group tended to gain more weight during the follow-up. The incidence of renal graft dysfunction was comparable (4/6 for BS-post-KTx, 3/5 for BS-pre-KTx) between groups. Conclusions: BS in patients with KTx appears to be safe and effective attending to metabolic and renal outcomes. These results seem irrespective of the time course, except for weight regain, which appears to be a common pattern in the BS-post-KTx group. MDPI 2022-10-13 /pmc/articles/PMC9604744/ /pubmed/36294351 http://dx.doi.org/10.3390/jcm11206030 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pané, Adriana
Molina-Andujar, Alicia
Olbeyra, Romina
Romano-Andrioni, Bárbara
Boswell, Laura
Montagud-Marrahi, Enrique
Jiménez, Amanda
Ibarzabal, Ainitze
Viaplana, Judith
Ventura-Aguiar, Pedro
Amor, Antonio J.
Vidal, Josep
Flores, Lilliam
de Hollanda, Ana
Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title_full Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title_fullStr Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title_full_unstemmed Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title_short Bariatric Surgery Outcomes in Patients with Kidney Transplantation
title_sort bariatric surgery outcomes in patients with kidney transplantation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604744/
https://www.ncbi.nlm.nih.gov/pubmed/36294351
http://dx.doi.org/10.3390/jcm11206030
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