Cargando…
Bariatric Surgery Outcomes in Patients with Kidney Transplantation
Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful ther...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604744/ https://www.ncbi.nlm.nih.gov/pubmed/36294351 http://dx.doi.org/10.3390/jcm11206030 |
_version_ | 1784817891753852928 |
---|---|
author | Pané, Adriana Molina-Andujar, Alicia Olbeyra, Romina Romano-Andrioni, Bárbara Boswell, Laura Montagud-Marrahi, Enrique Jiménez, Amanda Ibarzabal, Ainitze Viaplana, Judith Ventura-Aguiar, Pedro Amor, Antonio J. Vidal, Josep Flores, Lilliam de Hollanda, Ana |
author_facet | Pané, Adriana Molina-Andujar, Alicia Olbeyra, Romina Romano-Andrioni, Bárbara Boswell, Laura Montagud-Marrahi, Enrique Jiménez, Amanda Ibarzabal, Ainitze Viaplana, Judith Ventura-Aguiar, Pedro Amor, Antonio J. Vidal, Josep Flores, Lilliam de Hollanda, Ana |
author_sort | Pané, Adriana |
collection | PubMed |
description | Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful therapeutic tool either before or after KTx. Since evidence regarding the best approach is still scarce, we aimed to describe renal and metabolic outcomes in a single centre with more than 15-year experience in both surgeries. Methods: A retrospective study including patients who had received a KTx either before or after BS. Usual metabolic and renal outcomes, but also new variables (as renal graft dysfunction) were collected for a minimum follow-up of 1-year post-BS. Results: A total of 11 patients were included: n = 6 (BS-post-KTx) and n = 5 (BS-pre-KTx). One patient was assessed in both groups. No differences in the main outcomes were identified, but BS-post-KTx group tended to gain more weight during the follow-up. The incidence of renal graft dysfunction was comparable (4/6 for BS-post-KTx, 3/5 for BS-pre-KTx) between groups. Conclusions: BS in patients with KTx appears to be safe and effective attending to metabolic and renal outcomes. These results seem irrespective of the time course, except for weight regain, which appears to be a common pattern in the BS-post-KTx group. |
format | Online Article Text |
id | pubmed-9604744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96047442022-10-27 Bariatric Surgery Outcomes in Patients with Kidney Transplantation Pané, Adriana Molina-Andujar, Alicia Olbeyra, Romina Romano-Andrioni, Bárbara Boswell, Laura Montagud-Marrahi, Enrique Jiménez, Amanda Ibarzabal, Ainitze Viaplana, Judith Ventura-Aguiar, Pedro Amor, Antonio J. Vidal, Josep Flores, Lilliam de Hollanda, Ana J Clin Med Article Obesity and kidney transplantation (KTx) are closely related. Obesity increases the risk of chronic kidney disease and can be a relative contraindication for KTx. Besides, KTx recipients are predisposed to obesity and its comorbidities. Consequently, bariatric surgery (BS) emerges as a powerful therapeutic tool either before or after KTx. Since evidence regarding the best approach is still scarce, we aimed to describe renal and metabolic outcomes in a single centre with more than 15-year experience in both surgeries. Methods: A retrospective study including patients who had received a KTx either before or after BS. Usual metabolic and renal outcomes, but also new variables (as renal graft dysfunction) were collected for a minimum follow-up of 1-year post-BS. Results: A total of 11 patients were included: n = 6 (BS-post-KTx) and n = 5 (BS-pre-KTx). One patient was assessed in both groups. No differences in the main outcomes were identified, but BS-post-KTx group tended to gain more weight during the follow-up. The incidence of renal graft dysfunction was comparable (4/6 for BS-post-KTx, 3/5 for BS-pre-KTx) between groups. Conclusions: BS in patients with KTx appears to be safe and effective attending to metabolic and renal outcomes. These results seem irrespective of the time course, except for weight regain, which appears to be a common pattern in the BS-post-KTx group. MDPI 2022-10-13 /pmc/articles/PMC9604744/ /pubmed/36294351 http://dx.doi.org/10.3390/jcm11206030 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pané, Adriana Molina-Andujar, Alicia Olbeyra, Romina Romano-Andrioni, Bárbara Boswell, Laura Montagud-Marrahi, Enrique Jiménez, Amanda Ibarzabal, Ainitze Viaplana, Judith Ventura-Aguiar, Pedro Amor, Antonio J. Vidal, Josep Flores, Lilliam de Hollanda, Ana Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title | Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title_full | Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title_fullStr | Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title_full_unstemmed | Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title_short | Bariatric Surgery Outcomes in Patients with Kidney Transplantation |
title_sort | bariatric surgery outcomes in patients with kidney transplantation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604744/ https://www.ncbi.nlm.nih.gov/pubmed/36294351 http://dx.doi.org/10.3390/jcm11206030 |
work_keys_str_mv | AT paneadriana bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT molinaandujaralicia bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT olbeyraromina bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT romanoandrionibarbara bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT boswelllaura bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT montagudmarrahienrique bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT jimenezamanda bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT ibarzabalainitze bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT viaplanajudith bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT venturaaguiarpedro bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT amorantonioj bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT vidaljosep bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT floreslilliam bariatricsurgeryoutcomesinpatientswithkidneytransplantation AT dehollandaana bariatricsurgeryoutcomesinpatientswithkidneytransplantation |