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Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial
Violet light (VL), 360–400 nm wavelength, is contained in the sunlight and is an effective element for myopia suppression. This study is to investigate the safety and efficacy of novel eyeglasses that emit VL from the frames. This is a double-masked, randomized, pilot clinical trial conducted in a c...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604831/ https://www.ncbi.nlm.nih.gov/pubmed/36294321 http://dx.doi.org/10.3390/jcm11206000 |
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author | Torii, Hidemasa Mori, Kiwako Okano, Takashi Kondo, Shinichiro Yang, Hao-Yung Yotsukura, Erisa Hanyuda, Akiko Ogawa, Mamoru Negishi, Kazuno Kurihara, Toshihide Tsubota, Kazuo |
author_facet | Torii, Hidemasa Mori, Kiwako Okano, Takashi Kondo, Shinichiro Yang, Hao-Yung Yotsukura, Erisa Hanyuda, Akiko Ogawa, Mamoru Negishi, Kazuno Kurihara, Toshihide Tsubota, Kazuo |
author_sort | Torii, Hidemasa |
collection | PubMed |
description | Violet light (VL), 360–400 nm wavelength, is contained in the sunlight and is an effective element for myopia suppression. This study is to investigate the safety and efficacy of novel eyeglasses that emit VL from the frames. This is a double-masked, randomized, pilot clinical trial conducted in a clinic in Japan. Forty-three children with myopia were enrolled. Participants were randomly assigned to two groups, wearing VL-emitting eyeglass frames (VLf) that emitted VL of 310 μW/cm(2) (VLf group, n = 22) or pseudo-placebo eyeglass frames with a minimal emission of VL (<10 μW/cm(2)) (control group, n = 21). The exposure time was 3 h per day. The primary outcomes were visual acuity, tear film break-up time, corneal endothelial cell density, and the slit-lamp/fundus examinations. The secondary outcome was the 6-month changes in the axial lengths and cycloplegic refractions. Forty-one (95%) participants were included; twenty-one in the VLf group and twenty in the control group. No significant differences were seen in any safety evaluation. Significant changes were seen in axial elongation, choroidal thickness, and cycloplegic refractions in the subgroup analysis of 8- to 10-year-old children (p < 0.05), but otherwise no significant differences were seen. The VLf showed short-term safety and effectiveness against myopia progression. |
format | Online Article Text |
id | pubmed-9604831 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96048312022-10-27 Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial Torii, Hidemasa Mori, Kiwako Okano, Takashi Kondo, Shinichiro Yang, Hao-Yung Yotsukura, Erisa Hanyuda, Akiko Ogawa, Mamoru Negishi, Kazuno Kurihara, Toshihide Tsubota, Kazuo J Clin Med Article Violet light (VL), 360–400 nm wavelength, is contained in the sunlight and is an effective element for myopia suppression. This study is to investigate the safety and efficacy of novel eyeglasses that emit VL from the frames. This is a double-masked, randomized, pilot clinical trial conducted in a clinic in Japan. Forty-three children with myopia were enrolled. Participants were randomly assigned to two groups, wearing VL-emitting eyeglass frames (VLf) that emitted VL of 310 μW/cm(2) (VLf group, n = 22) or pseudo-placebo eyeglass frames with a minimal emission of VL (<10 μW/cm(2)) (control group, n = 21). The exposure time was 3 h per day. The primary outcomes were visual acuity, tear film break-up time, corneal endothelial cell density, and the slit-lamp/fundus examinations. The secondary outcome was the 6-month changes in the axial lengths and cycloplegic refractions. Forty-one (95%) participants were included; twenty-one in the VLf group and twenty in the control group. No significant differences were seen in any safety evaluation. Significant changes were seen in axial elongation, choroidal thickness, and cycloplegic refractions in the subgroup analysis of 8- to 10-year-old children (p < 0.05), but otherwise no significant differences were seen. The VLf showed short-term safety and effectiveness against myopia progression. MDPI 2022-10-11 /pmc/articles/PMC9604831/ /pubmed/36294321 http://dx.doi.org/10.3390/jcm11206000 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Torii, Hidemasa Mori, Kiwako Okano, Takashi Kondo, Shinichiro Yang, Hao-Yung Yotsukura, Erisa Hanyuda, Akiko Ogawa, Mamoru Negishi, Kazuno Kurihara, Toshihide Tsubota, Kazuo Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title | Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title_full | Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title_fullStr | Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title_full_unstemmed | Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title_short | Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial |
title_sort | short-term exposure to violet light emitted from eyeglass frames in myopic children: a randomized pilot clinical trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604831/ https://www.ncbi.nlm.nih.gov/pubmed/36294321 http://dx.doi.org/10.3390/jcm11206000 |
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