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The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis

Background: Lumbar epidural analgesia (EA) is the most commonly used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains a matter of debate. Our aim was to examine whether EA affected the course and the outcomes...

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Autores principales: Zanfini, Bruno Antonio, Catarci, Stefano, Vassalli, Francesco, Laurita Longo, Valentina, Biancone, Matteo, Carducci, Brigida, Frassanito, Luciano, Lanzone, Antonio, Draisci, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604843/
https://www.ncbi.nlm.nih.gov/pubmed/36294447
http://dx.doi.org/10.3390/jcm11206124
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author Zanfini, Bruno Antonio
Catarci, Stefano
Vassalli, Francesco
Laurita Longo, Valentina
Biancone, Matteo
Carducci, Brigida
Frassanito, Luciano
Lanzone, Antonio
Draisci, Gaetano
author_facet Zanfini, Bruno Antonio
Catarci, Stefano
Vassalli, Francesco
Laurita Longo, Valentina
Biancone, Matteo
Carducci, Brigida
Frassanito, Luciano
Lanzone, Antonio
Draisci, Gaetano
author_sort Zanfini, Bruno Antonio
collection PubMed
description Background: Lumbar epidural analgesia (EA) is the most commonly used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains a matter of debate. Our aim was to examine whether EA affected the course and the outcomes of labour among patients divided according to the Robson-10 group classification system. Methods: Patients of Robson’s classes 1, 2a, 3, and 4a were divided into either the EA group or the non-epidural analgesia (NEA) group. A propensity score-matching analysis was performed to balance the intergroup differences. The primary goal was to analyse the duration of the second stage of labour. The secondary goals were to evaluate neonatal and maternal outcomes. Results: In total, 21,808 cases were analysed. The second stage of labour for all groups was prolonged using EA (p < 0.05) without statistically significant differences in neonatal outcomes. EA resulted in a lower rate of episiotomies in nulliparous patients, with a higher rate of operative vaginal deliveries (OVD) (p < 0.05) and Caesarean sections (CS) (p < 0.05) in some classes. Conclusions: EA prolonged the duration of labour without affecting neonatal outcomes and reduced the rate of episiotomies, but also increased the rate of OVDs.
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spelling pubmed-96048432022-10-27 The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis Zanfini, Bruno Antonio Catarci, Stefano Vassalli, Francesco Laurita Longo, Valentina Biancone, Matteo Carducci, Brigida Frassanito, Luciano Lanzone, Antonio Draisci, Gaetano J Clin Med Article Background: Lumbar epidural analgesia (EA) is the most commonly used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains a matter of debate. Our aim was to examine whether EA affected the course and the outcomes of labour among patients divided according to the Robson-10 group classification system. Methods: Patients of Robson’s classes 1, 2a, 3, and 4a were divided into either the EA group or the non-epidural analgesia (NEA) group. A propensity score-matching analysis was performed to balance the intergroup differences. The primary goal was to analyse the duration of the second stage of labour. The secondary goals were to evaluate neonatal and maternal outcomes. Results: In total, 21,808 cases were analysed. The second stage of labour for all groups was prolonged using EA (p < 0.05) without statistically significant differences in neonatal outcomes. EA resulted in a lower rate of episiotomies in nulliparous patients, with a higher rate of operative vaginal deliveries (OVD) (p < 0.05) and Caesarean sections (CS) (p < 0.05) in some classes. Conclusions: EA prolonged the duration of labour without affecting neonatal outcomes and reduced the rate of episiotomies, but also increased the rate of OVDs. MDPI 2022-10-18 /pmc/articles/PMC9604843/ /pubmed/36294447 http://dx.doi.org/10.3390/jcm11206124 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zanfini, Bruno Antonio
Catarci, Stefano
Vassalli, Francesco
Laurita Longo, Valentina
Biancone, Matteo
Carducci, Brigida
Frassanito, Luciano
Lanzone, Antonio
Draisci, Gaetano
The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title_full The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title_fullStr The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title_full_unstemmed The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title_short The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson’s Classes: A Propensity Score-Matched Analysis
title_sort effect of epidural analgesia on labour and neonatal and maternal outcomes in 1, 2a, 3, and 4a robson’s classes: a propensity score-matched analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604843/
https://www.ncbi.nlm.nih.gov/pubmed/36294447
http://dx.doi.org/10.3390/jcm11206124
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