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Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives
Periodontitis is characterized by low-grade inflammation of the periodontal tissues, the structures that support and connect the teeth to the maxilla and mandible. This inflammation is caused by the accumulation of subgingival bacterial biofilm and gradually leads to the extensive damage of these ti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604856/ https://www.ncbi.nlm.nih.gov/pubmed/36294719 http://dx.doi.org/10.3390/jpm12101580 |
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author | Gheorghe, Dorin Nicolae Bennardo, Francesco Popescu, Dora Maria Nicolae, Flavia Mirela Ionele, Claudiu Marinel Boldeanu, Mihail Virgil Camen, Adrian Rogoveanu, Ion Surlin, Petra |
author_facet | Gheorghe, Dorin Nicolae Bennardo, Francesco Popescu, Dora Maria Nicolae, Flavia Mirela Ionele, Claudiu Marinel Boldeanu, Mihail Virgil Camen, Adrian Rogoveanu, Ion Surlin, Petra |
author_sort | Gheorghe, Dorin Nicolae |
collection | PubMed |
description | Periodontitis is characterized by low-grade inflammation of the periodontal tissues, the structures that support and connect the teeth to the maxilla and mandible. This inflammation is caused by the accumulation of subgingival bacterial biofilm and gradually leads to the extensive damage of these tissues and the consequent loss of teeth. Hepatitis B is a major global health concern; infection with the hepatitis B virus causes significant inflammation of the liver and the possibility of its gradual evolution to cirrhosis. Hepatitis D, caused by infection with the delta hepatitis virus, is manifest only in patients already infected with the type B virus in a simultaneous (co-infected) or superimposed (superinfected) manner. The dental and periodontal status of patients with hepatitis B/D could exhibit significant changes, increasing the risk of periodontitis onset. Moreover, the progression of liver changes in these patients could be linked to periodontitis; therefore, motivating good oral and periodontal health could result in the prevention and limitation of pathological effects. Given that both types of diseases have a significant inflammatory component, common pro-inflammatory mediators could drive and augment the local inflammation at both a periodontal and hepatic level. This suggests that integrated management of these patients should be proposed, as therapeutical means could deliver an improvement to both periodontal and hepatic statuses. The aim of this review is to gather existing information on the proposed subject and to organize significant data in order to improve scientific accuracy and comprehension on this topic while generating future perspectives for research. |
format | Online Article Text |
id | pubmed-9604856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96048562022-10-27 Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives Gheorghe, Dorin Nicolae Bennardo, Francesco Popescu, Dora Maria Nicolae, Flavia Mirela Ionele, Claudiu Marinel Boldeanu, Mihail Virgil Camen, Adrian Rogoveanu, Ion Surlin, Petra J Pers Med Review Periodontitis is characterized by low-grade inflammation of the periodontal tissues, the structures that support and connect the teeth to the maxilla and mandible. This inflammation is caused by the accumulation of subgingival bacterial biofilm and gradually leads to the extensive damage of these tissues and the consequent loss of teeth. Hepatitis B is a major global health concern; infection with the hepatitis B virus causes significant inflammation of the liver and the possibility of its gradual evolution to cirrhosis. Hepatitis D, caused by infection with the delta hepatitis virus, is manifest only in patients already infected with the type B virus in a simultaneous (co-infected) or superimposed (superinfected) manner. The dental and periodontal status of patients with hepatitis B/D could exhibit significant changes, increasing the risk of periodontitis onset. Moreover, the progression of liver changes in these patients could be linked to periodontitis; therefore, motivating good oral and periodontal health could result in the prevention and limitation of pathological effects. Given that both types of diseases have a significant inflammatory component, common pro-inflammatory mediators could drive and augment the local inflammation at both a periodontal and hepatic level. This suggests that integrated management of these patients should be proposed, as therapeutical means could deliver an improvement to both periodontal and hepatic statuses. The aim of this review is to gather existing information on the proposed subject and to organize significant data in order to improve scientific accuracy and comprehension on this topic while generating future perspectives for research. MDPI 2022-09-26 /pmc/articles/PMC9604856/ /pubmed/36294719 http://dx.doi.org/10.3390/jpm12101580 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gheorghe, Dorin Nicolae Bennardo, Francesco Popescu, Dora Maria Nicolae, Flavia Mirela Ionele, Claudiu Marinel Boldeanu, Mihail Virgil Camen, Adrian Rogoveanu, Ion Surlin, Petra Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title | Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title_full | Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title_fullStr | Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title_full_unstemmed | Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title_short | Oral and Periodontal Implications of Hepatitis Type B and D. Current State of Knowledge and Future Perspectives |
title_sort | oral and periodontal implications of hepatitis type b and d. current state of knowledge and future perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604856/ https://www.ncbi.nlm.nih.gov/pubmed/36294719 http://dx.doi.org/10.3390/jpm12101580 |
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