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Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review

Background: COVID-19 is a viral infectious disease leading to a spectrum of clinical complications, especially cardiovascular. Evidence shows that this infection can potentially accompany a worse outcome in pregnant women. Cardiovascular complications in mothers and their fetuses are reported by pre...

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Autores principales: Yaghoobpoor, Shirin, Fathi, Mobina, Vakili, Kimia, Tutunchian, Zohreh, Dehghani, Mina, Bahrami, Ashkan, Hajibeygi, Ramtin, Eslami, Samira, Yaghoobpour, Tina, Hajiesmaeili, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604883/
https://www.ncbi.nlm.nih.gov/pubmed/36294520
http://dx.doi.org/10.3390/jcm11206194
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author Yaghoobpoor, Shirin
Fathi, Mobina
Vakili, Kimia
Tutunchian, Zohreh
Dehghani, Mina
Bahrami, Ashkan
Hajibeygi, Ramtin
Eslami, Samira
Yaghoobpour, Tina
Hajiesmaeili, Mohammadreza
author_facet Yaghoobpoor, Shirin
Fathi, Mobina
Vakili, Kimia
Tutunchian, Zohreh
Dehghani, Mina
Bahrami, Ashkan
Hajibeygi, Ramtin
Eslami, Samira
Yaghoobpour, Tina
Hajiesmaeili, Mohammadreza
author_sort Yaghoobpoor, Shirin
collection PubMed
description Background: COVID-19 is a viral infectious disease leading to a spectrum of clinical complications, especially cardiovascular. Evidence shows that this infection can potentially accompany a worse outcome in pregnant women. Cardiovascular complications in mothers and their fetuses are reported by previous studies. Objective: In this systematic review, we aim to investigate the cardiovascular complications of COVID-19 during pregnancy in the mothers and fetus, according to the published literature. Method: We systematically searched the online databases of PubMed, Scopus, Web of Science, and Google Scholar, using relevant keywords up to April 2022. We included all observational studies reporting cardiovascular complications among COVID-19-affected pregnant women and their fetuses. Results: We included 74 studies containing 47582 pregnant COVID-19 cases. Pre-eclampsia, hypertensive disorders, cardiomyopathy, heart failure, myocardial infarction, thrombosis formation, alterations in maternal–fetal Doppler patterns, and maternal and fetal arrhythmia were reported as cardiovascular complications. The highest incidences of pre-eclampsia/eclampsia among COVID-19 pregnant cases, reported by studies, were 69% and 62%, and the lowest were 0.5% and 3%. The highest and lowest incidences of fetal bradycardia were 20% and 3%, and regarding fetal tachycardia, 5.4% and 1%, respectively. Conclusion: SARS-CoV-2 infection during pregnancy can potentially be associated with cardiovascular complications in the mother, particularly pre-eclampsia and heart failure. Moreover, SARS-CoV-2 infection during pregnancy can potentially cause cardiovascular complications in the fetus, particularly arrhythmia.
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spelling pubmed-96048832022-10-27 Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review Yaghoobpoor, Shirin Fathi, Mobina Vakili, Kimia Tutunchian, Zohreh Dehghani, Mina Bahrami, Ashkan Hajibeygi, Ramtin Eslami, Samira Yaghoobpour, Tina Hajiesmaeili, Mohammadreza J Clin Med Systematic Review Background: COVID-19 is a viral infectious disease leading to a spectrum of clinical complications, especially cardiovascular. Evidence shows that this infection can potentially accompany a worse outcome in pregnant women. Cardiovascular complications in mothers and their fetuses are reported by previous studies. Objective: In this systematic review, we aim to investigate the cardiovascular complications of COVID-19 during pregnancy in the mothers and fetus, according to the published literature. Method: We systematically searched the online databases of PubMed, Scopus, Web of Science, and Google Scholar, using relevant keywords up to April 2022. We included all observational studies reporting cardiovascular complications among COVID-19-affected pregnant women and their fetuses. Results: We included 74 studies containing 47582 pregnant COVID-19 cases. Pre-eclampsia, hypertensive disorders, cardiomyopathy, heart failure, myocardial infarction, thrombosis formation, alterations in maternal–fetal Doppler patterns, and maternal and fetal arrhythmia were reported as cardiovascular complications. The highest incidences of pre-eclampsia/eclampsia among COVID-19 pregnant cases, reported by studies, were 69% and 62%, and the lowest were 0.5% and 3%. The highest and lowest incidences of fetal bradycardia were 20% and 3%, and regarding fetal tachycardia, 5.4% and 1%, respectively. Conclusion: SARS-CoV-2 infection during pregnancy can potentially be associated with cardiovascular complications in the mother, particularly pre-eclampsia and heart failure. Moreover, SARS-CoV-2 infection during pregnancy can potentially cause cardiovascular complications in the fetus, particularly arrhythmia. MDPI 2022-10-20 /pmc/articles/PMC9604883/ /pubmed/36294520 http://dx.doi.org/10.3390/jcm11206194 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Yaghoobpoor, Shirin
Fathi, Mobina
Vakili, Kimia
Tutunchian, Zohreh
Dehghani, Mina
Bahrami, Ashkan
Hajibeygi, Ramtin
Eslami, Samira
Yaghoobpour, Tina
Hajiesmaeili, Mohammadreza
Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title_full Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title_fullStr Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title_full_unstemmed Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title_short Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review
title_sort cardiovascular complications of covid-19 among pregnant women and their fetuses: a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604883/
https://www.ncbi.nlm.nih.gov/pubmed/36294520
http://dx.doi.org/10.3390/jcm11206194
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