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Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientifi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604902/ https://www.ncbi.nlm.nih.gov/pubmed/36294391 http://dx.doi.org/10.3390/jcm11206072 |
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author | Slyamova, Gulnur Gusmanov, Arnur Batpenov, Arman Kaliev, Nurlan Viderman, Dmitriy |
author_facet | Slyamova, Gulnur Gusmanov, Arnur Batpenov, Arman Kaliev, Nurlan Viderman, Dmitriy |
author_sort | Slyamova, Gulnur |
collection | PubMed |
description | The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientific Center of Traumatology and Orthopedics from 2018 to 2020. Cases were matched with controls in a 1:4 ratio. Exact matching was performed by gender, ICD-10, and ICD-9 codes. The main variables included socio-demographics, diagnosis at admission, characteristics of fractures, comorbidities, complications, hospitalization milestones, and osteomyelitis characteristics. Descriptive analyses, along with bivariate analysis and multivariate conditional logistic regression, were performed. Open fracture (adjOR = 6.25; 95%CI 1.64–23.79), the presence of complications of initial fracture (adjOR = 3.46, 95%CI 1.13–10.56), comminuted fracture form (adjOR = 1.87; 95%CI 0.73–4.75), a positive history of diabetes or blood glucose >7 g/L (adjOR = 4.25; 95%CI 1.26–14.3), incision or wound length of more than 10 cm (adjOR = 6.53; 95%CI 1.1–38.6), additional implanted medical item (adjOR = 1.23; 95% CI 1.1–1.47), and unemployment or being retired (adjOR = 4.21; 95%CI 1.74–10.18) were found to be significant predictors of postoperative osteomyelitis. Almost all our findings are concordant with previous studies, except for the type of fracture. Different authors report conflicting results on the latter potential risk factor. Therefore, prospective studies on this issue are required. |
format | Online Article Text |
id | pubmed-9604902 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96049022022-10-27 Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study Slyamova, Gulnur Gusmanov, Arnur Batpenov, Arman Kaliev, Nurlan Viderman, Dmitriy J Clin Med Article The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientific Center of Traumatology and Orthopedics from 2018 to 2020. Cases were matched with controls in a 1:4 ratio. Exact matching was performed by gender, ICD-10, and ICD-9 codes. The main variables included socio-demographics, diagnosis at admission, characteristics of fractures, comorbidities, complications, hospitalization milestones, and osteomyelitis characteristics. Descriptive analyses, along with bivariate analysis and multivariate conditional logistic regression, were performed. Open fracture (adjOR = 6.25; 95%CI 1.64–23.79), the presence of complications of initial fracture (adjOR = 3.46, 95%CI 1.13–10.56), comminuted fracture form (adjOR = 1.87; 95%CI 0.73–4.75), a positive history of diabetes or blood glucose >7 g/L (adjOR = 4.25; 95%CI 1.26–14.3), incision or wound length of more than 10 cm (adjOR = 6.53; 95%CI 1.1–38.6), additional implanted medical item (adjOR = 1.23; 95% CI 1.1–1.47), and unemployment or being retired (adjOR = 4.21; 95%CI 1.74–10.18) were found to be significant predictors of postoperative osteomyelitis. Almost all our findings are concordant with previous studies, except for the type of fracture. Different authors report conflicting results on the latter potential risk factor. Therefore, prospective studies on this issue are required. MDPI 2022-10-14 /pmc/articles/PMC9604902/ /pubmed/36294391 http://dx.doi.org/10.3390/jcm11206072 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Slyamova, Gulnur Gusmanov, Arnur Batpenov, Arman Kaliev, Nurlan Viderman, Dmitriy Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title | Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title_full | Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title_fullStr | Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title_full_unstemmed | Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title_short | Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study |
title_sort | risk factors for postoperative osteomyelitis among patients after bone fracture: a matched case–control study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604902/ https://www.ncbi.nlm.nih.gov/pubmed/36294391 http://dx.doi.org/10.3390/jcm11206072 |
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