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Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study

The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientifi...

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Autores principales: Slyamova, Gulnur, Gusmanov, Arnur, Batpenov, Arman, Kaliev, Nurlan, Viderman, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604902/
https://www.ncbi.nlm.nih.gov/pubmed/36294391
http://dx.doi.org/10.3390/jcm11206072
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author Slyamova, Gulnur
Gusmanov, Arnur
Batpenov, Arman
Kaliev, Nurlan
Viderman, Dmitriy
author_facet Slyamova, Gulnur
Gusmanov, Arnur
Batpenov, Arman
Kaliev, Nurlan
Viderman, Dmitriy
author_sort Slyamova, Gulnur
collection PubMed
description The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientific Center of Traumatology and Orthopedics from 2018 to 2020. Cases were matched with controls in a 1:4 ratio. Exact matching was performed by gender, ICD-10, and ICD-9 codes. The main variables included socio-demographics, diagnosis at admission, characteristics of fractures, comorbidities, complications, hospitalization milestones, and osteomyelitis characteristics. Descriptive analyses, along with bivariate analysis and multivariate conditional logistic regression, were performed. Open fracture (adjOR = 6.25; 95%CI 1.64–23.79), the presence of complications of initial fracture (adjOR = 3.46, 95%CI 1.13–10.56), comminuted fracture form (adjOR = 1.87; 95%CI 0.73–4.75), a positive history of diabetes or blood glucose >7 g/L (adjOR = 4.25; 95%CI 1.26–14.3), incision or wound length of more than 10 cm (adjOR = 6.53; 95%CI 1.1–38.6), additional implanted medical item (adjOR = 1.23; 95% CI 1.1–1.47), and unemployment or being retired (adjOR = 4.21; 95%CI 1.74–10.18) were found to be significant predictors of postoperative osteomyelitis. Almost all our findings are concordant with previous studies, except for the type of fracture. Different authors report conflicting results on the latter potential risk factor. Therefore, prospective studies on this issue are required.
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spelling pubmed-96049022022-10-27 Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study Slyamova, Gulnur Gusmanov, Arnur Batpenov, Arman Kaliev, Nurlan Viderman, Dmitriy J Clin Med Article The healthcare burden of osteomyelitis is increasing. Postoperative and posttraumatic osteomyelitis account for 80% of all cases of osteomyelitis. The aim of this study was to find risk factors for postoperative osteomyelitis in Kazakhstan. We included 245 patients admitted to the National Scientific Center of Traumatology and Orthopedics from 2018 to 2020. Cases were matched with controls in a 1:4 ratio. Exact matching was performed by gender, ICD-10, and ICD-9 codes. The main variables included socio-demographics, diagnosis at admission, characteristics of fractures, comorbidities, complications, hospitalization milestones, and osteomyelitis characteristics. Descriptive analyses, along with bivariate analysis and multivariate conditional logistic regression, were performed. Open fracture (adjOR = 6.25; 95%CI 1.64–23.79), the presence of complications of initial fracture (adjOR = 3.46, 95%CI 1.13–10.56), comminuted fracture form (adjOR = 1.87; 95%CI 0.73–4.75), a positive history of diabetes or blood glucose >7 g/L (adjOR = 4.25; 95%CI 1.26–14.3), incision or wound length of more than 10 cm (adjOR = 6.53; 95%CI 1.1–38.6), additional implanted medical item (adjOR = 1.23; 95% CI 1.1–1.47), and unemployment or being retired (adjOR = 4.21; 95%CI 1.74–10.18) were found to be significant predictors of postoperative osteomyelitis. Almost all our findings are concordant with previous studies, except for the type of fracture. Different authors report conflicting results on the latter potential risk factor. Therefore, prospective studies on this issue are required. MDPI 2022-10-14 /pmc/articles/PMC9604902/ /pubmed/36294391 http://dx.doi.org/10.3390/jcm11206072 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Slyamova, Gulnur
Gusmanov, Arnur
Batpenov, Arman
Kaliev, Nurlan
Viderman, Dmitriy
Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title_full Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title_fullStr Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title_full_unstemmed Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title_short Risk Factors for Postoperative Osteomyelitis among Patients after Bone Fracture: A Matched Case–Control Study
title_sort risk factors for postoperative osteomyelitis among patients after bone fracture: a matched case–control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604902/
https://www.ncbi.nlm.nih.gov/pubmed/36294391
http://dx.doi.org/10.3390/jcm11206072
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