Cargando…

Increased Carotid Intima-Media Thickness in Asymptomatic Individuals Is Associated with the PCSK9 (rs2149041) Gene Polymorphism in the Mexican Mestizo Population: Results of the GEA Cohort

The increase in carotid intima-media thickness (CIMT) and coronary artery calcification (CAC) are features of subclinical atherosclerosis that might be determined by the genetic background of patients. Among the multiple risk factors, the proprotein convertase subtilisin kexin type 9 (PCSK9) has a g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Posadas-Sánchez, Rosalinda, Vargas-Alarcón, Gilberto, Pérez-Méndez, Óscar, Pérez-Hernández, Nonanzit, Rodríguez-Pérez, José Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604912/ https://www.ncbi.nlm.nih.gov/pubmed/36294964 http://dx.doi.org/10.3390/life12101531

Ejemplares similares

Variants of PCSK9 Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project
por: Zamarrón-Licona, Erasmo, et al.
Publicado: (2021)

Osteoprotegerin Gene Polymorphisms Are Associated with Subclinical Atherosclerosis in the Mexican Mestizo Population
por: Cazarín-Santos, Benny Giovanni, et al.
Publicado: (2022)

Interleukin-27 polymorphisms are associated with premature coronary artery disease and metabolic parameters in the Mexican population: the genetics of atherosclerotic disease (GEA) Mexican study
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2017)

MRE11A Polymorphisms Are Associated With Subclinical Atherosclerosis and Cardiovascular Risk Factors. A Case-Control Study of the GEA Mexican Project
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2019)

Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2018)

Association of the rs17574 DPP4 Polymorphism with Premature Coronary Artery Disease in Diabetic Patients: Results from the Cohort of the GEA Mexican Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2022)

Interleukin-17A Gene Haplotypes Are Associated with Risk of Premature Coronary Artery Disease in Mexican Patients from the Genetics of Atherosclerotic Disease (GEA) Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2015)

IL-37 Gene and Cholesterol Metabolism: Association of Polymorphisms with the Presence of Hypercholesterolemia and Cardiovascular Risk Factors. The GEA Mexican Study
por: López-Bautista, Fabiola, et al.
Publicado: (2020)

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls—The GEA Mexican Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2022)

Serum magnesium is inversely associated with coronary artery calcification in the Genetics of Atherosclerotic Disease (GEA) study
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2016)

Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2017)

Association of the IL-37 Polymorphisms with Transaminases and Alkaline Phosphatase Levels in Premature Coronary Artery Disease Patients and Healthy Controls. Results of the Genetics of Atherosclerotic (GEA) Mexican Study
por: López-Bautista, Fabiola, et al.
Publicado: (2021)

A haplotype of the phosphodiesterase 4D (PDE4D) gene is associated with myocardial infarction and with cardiometabolic parameters: the GEA study
por: Rodríguez-Pérez, José Manuel, et al.
Publicado: (2018)

The rs508487, rs236911, and rs236918 Genetic Variants of the Proprotein Convertase Subtilisin–Kexin Type 7 (PCSK7) Gene Are Associated with Acute Coronary Syndrome and with Plasma Concentrations of HDL-Cholesterol and Triglycerides
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2021)

Interferon Regulatory Factor 5 (IRF5) Gene Haplotypes Are Associated with Premature Coronary Artery Disease. Association of the IRF5 Polymorphisms with Cardiometabolic Parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican Study
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2021)

Common Variants in IL-20 Gene are Associated with Subclinical Atherosclerosis, Cardiovascular Risk Factors and IL-20 Levels in the Cohort of the Genetics of Atherosclerotic Disease (GEA) Mexican Study
por: Angeles-Martínez, Javier, et al.
Publicado: (2020)

PHACTR1 Gene Polymorphism Is Associated with Increased Risk of Developing Premature Coronary Artery Disease in Mexican Population
por: Pérez-Hernández, Nonanzit, et al.
Publicado: (2016)

The (G>A) rs11573191 Polymorphism of PLA2G5 Gene Is Associated with Premature Coronary Artery Disease in the Mexican Mestizo Population: The Genetics of Atherosclerotic Disease Mexican Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2014)

The −44 C/G (rs1800972) polymorphism of the β‐defensin 1 is associated with increased risk of developing type 2 diabetes mellitus
por: Martinez‐Rios, Marco Antonio, et al.
Publicado: (2018)

Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2013)

Autoimmune vitiligo in rheumatic disease in the mestizo Mexican population
por: Avalos-Díaz, Esperanza, et al.
Publicado: (2016)

Correction: Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2013)

Self-perceived stress is associated with adiposity and atherosclerosis. The GEA Study
por: Ortega-Montiel, Janinne, et al.
Publicado: (2015)

The rs12617336 and rs17574 Dipeptidyl Peptidase-4 Polymorphisms Are Associated With Hypoalphalipoproteinemia and Dipeptidyl Peptidase-4 Serum Levels: A Case-Control Study of the Genetics of Atherosclerotic Disease (GEA) Cohort
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2021)

The rs4783961 and rs708272 genetic variants of the CETP gene are associated with coronary artery disease, but not with restenosis after coronary stenting
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2022)

IL10 rs1800872 Is Associated with Non-Steroidal Anti-Inflammatory Drugs Exacerbated Respiratory Disease in Mexican-Mestizo Patients
por: Pavón-Romero, Gandhi Fernando, et al.
Publicado: (2020)

Hypomethylation of AHRR (cg05575921) Is Related to Smoking Status in the Mexican Mestizo Population
por: Bravo-Gutiérrez, Omar Andrés, et al.
Publicado: (2021)

The rs10455872-G allele of the LPA gene is associated with high lipoprotein(a) levels and increased aortic valve calcium in a Mexican adult population
por: Cardoso-Saldaña, Guillermo, et al.
Publicado: (2019)

Tamoxifen side effects: pharmacogenetic and clinical approach in Mexican mestizos
por: Rangel-Méndez, Jorge-Aarón, et al.
Publicado: (2019)

Osteopontin Gene Polymorphisms Are Associated with Cardiovascular Risk Factors in Patients with Premature Coronary Artery Disease
por: Pérez-Hernández, Nonanzit, et al.
Publicado: (2021)

The rs7044343 Polymorphism of the Interleukin 33 Gene Is Associated with Decreased Risk of Developing Premature Coronary Artery Disease and Central Obesity, and Could Be Involved in Regulating the Production of IL-33
por: Angeles-Martínez, Javier, et al.
Publicado: (2017)

Arsenic exposure and risk of preeclampsia in a Mexican mestizo population
por: Sandoval-Carrillo, Ada, et al.
Publicado: (2016)

Polymorphisms associated with the risk of lung cancer in a healthy Mexican Mestizo population: Application of the additive model for cancer
por: Pérez-Morales, Rebeca, et al.
Publicado: (2011)

Pregnancy Loss and Carotid Intima–Media Thickness in Mexican Women
por: Hartasanchez, Sandra A., et al.
Publicado: (2018)

Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos
por: García-Chapa, Eiralí Guadalupe, et al.
Publicado: (2017)

PCSK1 rs6232 Is Associated with Childhood and Adult Class III Obesity in the Mexican Population
por: Villalobos-Comparán, Marisela, et al.
Publicado: (2012)

Los mestizos de América
por: Pérez de Barradas, José
Publicado: (1948)

SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population
por: Vargas-Alarcon, Gilberto, et al.
Publicado: (2019)

Exposure to Violence and Carotid Artery Intima‐Media Thickness in Mexican Women
por: Flores‐Torres, Mario H., et al.
Publicado: (2017)

Visceral adipose tissue is an independent predictor and mediator of the progression of coronary calcification: a prospective sub-analysis of the GEA study
por: Antonio-Villa, Neftali Eduardo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lh8ge6r9cr8f40thgc8qfa7ihl