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Remdesivir does not affect mitochondrial DNA copy number or deletion mutation frequency in aged male rats: A short report

Remdesivir is a leading therapy in patients with moderate to severe coronavirus 2 (SARS-CoV-2) infection; the majority of whom are older individuals. Remdesivir is a nucleoside analog that incorporates into nascent viral RNA, inhibiting RNA-directed RNA polymerases, including that of SARS-CoV-2. Les...

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Detalles Bibliográficos
Autores principales:	Herbst, Allen, Choi, Solbie, Hoang, Austin N., Kim, Chiye, Martinez Moreno, Diana, McKenzie, Debbie, Aiken, Judd M., Wanagat, Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605030/ https://www.ncbi.nlm.nih.gov/pubmed/36288327 http://dx.doi.org/10.1371/journal.pone.0271850

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