Cargando…

An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic

The “blue shark”, Prionace glauca (class: Chondrichthyes), is a pelagic shark species commonly found in tropical and temperate oceans. This shark is mainly sold in Asian countries as food and as traditional Chinese medicine. According to the Red List of the International Union for the Conservation o...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Wen-Chien, Chiu, Chien-Shan, Chan, Yung-Jia, Guo, Tian-Pin, Lin, Ching-Chin, Wang, Po-Chun, Lin, Po-Yu, Mulio, Amanda Tresiliana, Li, Po-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605125/
https://www.ncbi.nlm.nih.gov/pubmed/36286457
http://dx.doi.org/10.3390/md20100633
_version_ 1784817987544416256
author Lu, Wen-Chien
Chiu, Chien-Shan
Chan, Yung-Jia
Guo, Tian-Pin
Lin, Ching-Chin
Wang, Po-Chun
Lin, Po-Yu
Mulio, Amanda Tresiliana
Li, Po-Hsien
author_facet Lu, Wen-Chien
Chiu, Chien-Shan
Chan, Yung-Jia
Guo, Tian-Pin
Lin, Ching-Chin
Wang, Po-Chun
Lin, Po-Yu
Mulio, Amanda Tresiliana
Li, Po-Hsien
author_sort Lu, Wen-Chien
collection PubMed
description The “blue shark”, Prionace glauca (class: Chondrichthyes), is a pelagic shark species commonly found in tropical and temperate oceans. This shark is mainly sold in Asian countries as food and as traditional Chinese medicine. According to the Red List of the International Union for the Conservation of Nature, P. glauca is classified as low-risk to near endangered. P. glauca cartilage contains collagen type II, which makes it suitable as a bioactive ingredient in cosmeceutical products. This study evaluated the effects of a gel containing various concentrations (0.125–5%) of lyophilized hydrolyzed P. glauca cartilage on the human inner wrist skin compared to a placebo (base). A skin properties evaluation test was conducted before and after applying various concentrations (0.125–5%) of the P. glauca cartilage gel for 10 and 20 min on the inner wrists of participants using a skin analyzer that determined the moisture level, oil level, texture level, complexion level, and the 3D level. Adding lyophilized hydrolyzed shark cartilage (LHSC) significantly improved the moisture, texture, and complexion of the skin while controlling oil and providing a wrinkle-smoothing effect. The result indicated that LHSC formulations were prepared at different concentrations, and they had significantly enhanced effects on skin hydration and elasticity (texture) and the smoothing of wrinkles (3D level). The LHSC also effectively controlled oil secretion and the complexion.
format Online
Article
Text
id pubmed-9605125
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96051252022-10-27 An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic Lu, Wen-Chien Chiu, Chien-Shan Chan, Yung-Jia Guo, Tian-Pin Lin, Ching-Chin Wang, Po-Chun Lin, Po-Yu Mulio, Amanda Tresiliana Li, Po-Hsien Mar Drugs Article The “blue shark”, Prionace glauca (class: Chondrichthyes), is a pelagic shark species commonly found in tropical and temperate oceans. This shark is mainly sold in Asian countries as food and as traditional Chinese medicine. According to the Red List of the International Union for the Conservation of Nature, P. glauca is classified as low-risk to near endangered. P. glauca cartilage contains collagen type II, which makes it suitable as a bioactive ingredient in cosmeceutical products. This study evaluated the effects of a gel containing various concentrations (0.125–5%) of lyophilized hydrolyzed P. glauca cartilage on the human inner wrist skin compared to a placebo (base). A skin properties evaluation test was conducted before and after applying various concentrations (0.125–5%) of the P. glauca cartilage gel for 10 and 20 min on the inner wrists of participants using a skin analyzer that determined the moisture level, oil level, texture level, complexion level, and the 3D level. Adding lyophilized hydrolyzed shark cartilage (LHSC) significantly improved the moisture, texture, and complexion of the skin while controlling oil and providing a wrinkle-smoothing effect. The result indicated that LHSC formulations were prepared at different concentrations, and they had significantly enhanced effects on skin hydration and elasticity (texture) and the smoothing of wrinkles (3D level). The LHSC also effectively controlled oil secretion and the complexion. MDPI 2022-10-05 /pmc/articles/PMC9605125/ /pubmed/36286457 http://dx.doi.org/10.3390/md20100633 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lu, Wen-Chien
Chiu, Chien-Shan
Chan, Yung-Jia
Guo, Tian-Pin
Lin, Ching-Chin
Wang, Po-Chun
Lin, Po-Yu
Mulio, Amanda Tresiliana
Li, Po-Hsien
An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title_full An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title_fullStr An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title_full_unstemmed An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title_short An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic
title_sort in vivo study to evaluate the efficacy of blue shark (prionace glauca) cartilage collagen as a cosmetic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605125/
https://www.ncbi.nlm.nih.gov/pubmed/36286457
http://dx.doi.org/10.3390/md20100633
work_keys_str_mv AT luwenchien aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT chiuchienshan aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT chanyungjia aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT guotianpin aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT linchingchin aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT wangpochun aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT linpoyu aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT mulioamandatresiliana aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT lipohsien aninvivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT luwenchien invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT chiuchienshan invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT chanyungjia invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT guotianpin invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT linchingchin invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT wangpochun invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT linpoyu invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT mulioamandatresiliana invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic
AT lipohsien invivostudytoevaluatetheefficacyofbluesharkprionaceglaucacartilagecollagenasacosmetic