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Towards Precision Oncology: The Role of Smoothened and Its Variants in Cancer
The G protein-coupled receptor Smoothened (Smo) is a central signal transducer of the Hedgehog (Hh) pathway which has been linked to diverse forms of tumours. Stimulated by advancements in structural and functional characterisation, the Smo receptor has been recognised as an important therapeutic ta...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605185/ https://www.ncbi.nlm.nih.gov/pubmed/36294790 http://dx.doi.org/10.3390/jpm12101648 |