Cargando…

Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene

Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooke...

Descripción completa

Detalles Bibliográficos
Autores principales: Papakonstantinou, Panteleimon E., Benia, Dimitra, Polyzos, Dimitrios, Papakonstantinou, Konstantinos, Rorris, Filippos-Paschalis, Toulgaridis, Fotios, Manousiadis, Konstantinos, Xydonas, Sotirios, Sideris, Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605429/
https://www.ncbi.nlm.nih.gov/pubmed/36294947
http://dx.doi.org/10.3390/life12101511
_version_ 1784818064393502720
author Papakonstantinou, Panteleimon E.
Benia, Dimitra
Polyzos, Dimitrios
Papakonstantinou, Konstantinos
Rorris, Filippos-Paschalis
Toulgaridis, Fotios
Manousiadis, Konstantinos
Xydonas, Sotirios
Sideris, Antonios
author_facet Papakonstantinou, Panteleimon E.
Benia, Dimitra
Polyzos, Dimitrios
Papakonstantinou, Konstantinos
Rorris, Filippos-Paschalis
Toulgaridis, Fotios
Manousiadis, Konstantinos
Xydonas, Sotirios
Sideris, Antonios
author_sort Papakonstantinou, Panteleimon E.
collection PubMed
description Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooked, although it concerns a wide spectrum of patients surviving an acute event. Acute AD survivors ultimately enter a chronic aortic disease course. Patients with chronic thoracic AD (CTAD) require lifelong surveillance and a proportion of them may present with symptoms and late complications demanding further surgical or endovascular treatment. However, the available data concerning the management of CTAD is sparse in the literature. The management of patients with CTAD is challenging as far as determining the best medical therapy and deciding on intervention are concerned. Until recently, there were no guidelines or recommendations for imaging surveillance in patients with chronic AD. The diagnostic methods for imaging aortic diseases have been improved, while the data on new endovascular and surgical approaches has increased significantly. In this review, we summarize the current evidence in the diagnosis and management of CTAD and the latest recommendations for the surgical/endovascular aortic repair of CTAD.
format Online
Article
Text
id pubmed-9605429
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96054292022-10-27 Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene Papakonstantinou, Panteleimon E. Benia, Dimitra Polyzos, Dimitrios Papakonstantinou, Konstantinos Rorris, Filippos-Paschalis Toulgaridis, Fotios Manousiadis, Konstantinos Xydonas, Sotirios Sideris, Antonios Life (Basel) Review Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooked, although it concerns a wide spectrum of patients surviving an acute event. Acute AD survivors ultimately enter a chronic aortic disease course. Patients with chronic thoracic AD (CTAD) require lifelong surveillance and a proportion of them may present with symptoms and late complications demanding further surgical or endovascular treatment. However, the available data concerning the management of CTAD is sparse in the literature. The management of patients with CTAD is challenging as far as determining the best medical therapy and deciding on intervention are concerned. Until recently, there were no guidelines or recommendations for imaging surveillance in patients with chronic AD. The diagnostic methods for imaging aortic diseases have been improved, while the data on new endovascular and surgical approaches has increased significantly. In this review, we summarize the current evidence in the diagnosis and management of CTAD and the latest recommendations for the surgical/endovascular aortic repair of CTAD. MDPI 2022-09-28 /pmc/articles/PMC9605429/ /pubmed/36294947 http://dx.doi.org/10.3390/life12101511 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Papakonstantinou, Panteleimon E.
Benia, Dimitra
Polyzos, Dimitrios
Papakonstantinou, Konstantinos
Rorris, Filippos-Paschalis
Toulgaridis, Fotios
Manousiadis, Konstantinos
Xydonas, Sotirios
Sideris, Antonios
Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title_full Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title_fullStr Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title_full_unstemmed Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title_short Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
title_sort chronic thoracic aortic dissection: how to treat, when to intervene
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605429/
https://www.ncbi.nlm.nih.gov/pubmed/36294947
http://dx.doi.org/10.3390/life12101511
work_keys_str_mv AT papakonstantinoupanteleimone chronicthoracicaorticdissectionhowtotreatwhentointervene
AT beniadimitra chronicthoracicaorticdissectionhowtotreatwhentointervene
AT polyzosdimitrios chronicthoracicaorticdissectionhowtotreatwhentointervene
AT papakonstantinoukonstantinos chronicthoracicaorticdissectionhowtotreatwhentointervene
AT rorrisfilippospaschalis chronicthoracicaorticdissectionhowtotreatwhentointervene
AT toulgaridisfotios chronicthoracicaorticdissectionhowtotreatwhentointervene
AT manousiadiskonstantinos chronicthoracicaorticdissectionhowtotreatwhentointervene
AT xydonassotirios chronicthoracicaorticdissectionhowtotreatwhentointervene
AT siderisantonios chronicthoracicaorticdissectionhowtotreatwhentointervene