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Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene
Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooke...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605429/ https://www.ncbi.nlm.nih.gov/pubmed/36294947 http://dx.doi.org/10.3390/life12101511 |
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author | Papakonstantinou, Panteleimon E. Benia, Dimitra Polyzos, Dimitrios Papakonstantinou, Konstantinos Rorris, Filippos-Paschalis Toulgaridis, Fotios Manousiadis, Konstantinos Xydonas, Sotirios Sideris, Antonios |
author_facet | Papakonstantinou, Panteleimon E. Benia, Dimitra Polyzos, Dimitrios Papakonstantinou, Konstantinos Rorris, Filippos-Paschalis Toulgaridis, Fotios Manousiadis, Konstantinos Xydonas, Sotirios Sideris, Antonios |
author_sort | Papakonstantinou, Panteleimon E. |
collection | PubMed |
description | Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooked, although it concerns a wide spectrum of patients surviving an acute event. Acute AD survivors ultimately enter a chronic aortic disease course. Patients with chronic thoracic AD (CTAD) require lifelong surveillance and a proportion of them may present with symptoms and late complications demanding further surgical or endovascular treatment. However, the available data concerning the management of CTAD is sparse in the literature. The management of patients with CTAD is challenging as far as determining the best medical therapy and deciding on intervention are concerned. Until recently, there were no guidelines or recommendations for imaging surveillance in patients with chronic AD. The diagnostic methods for imaging aortic diseases have been improved, while the data on new endovascular and surgical approaches has increased significantly. In this review, we summarize the current evidence in the diagnosis and management of CTAD and the latest recommendations for the surgical/endovascular aortic repair of CTAD. |
format | Online Article Text |
id | pubmed-9605429 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96054292022-10-27 Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene Papakonstantinou, Panteleimon E. Benia, Dimitra Polyzos, Dimitrios Papakonstantinou, Konstantinos Rorris, Filippos-Paschalis Toulgaridis, Fotios Manousiadis, Konstantinos Xydonas, Sotirios Sideris, Antonios Life (Basel) Review Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooked, although it concerns a wide spectrum of patients surviving an acute event. Acute AD survivors ultimately enter a chronic aortic disease course. Patients with chronic thoracic AD (CTAD) require lifelong surveillance and a proportion of them may present with symptoms and late complications demanding further surgical or endovascular treatment. However, the available data concerning the management of CTAD is sparse in the literature. The management of patients with CTAD is challenging as far as determining the best medical therapy and deciding on intervention are concerned. Until recently, there were no guidelines or recommendations for imaging surveillance in patients with chronic AD. The diagnostic methods for imaging aortic diseases have been improved, while the data on new endovascular and surgical approaches has increased significantly. In this review, we summarize the current evidence in the diagnosis and management of CTAD and the latest recommendations for the surgical/endovascular aortic repair of CTAD. MDPI 2022-09-28 /pmc/articles/PMC9605429/ /pubmed/36294947 http://dx.doi.org/10.3390/life12101511 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Papakonstantinou, Panteleimon E. Benia, Dimitra Polyzos, Dimitrios Papakonstantinou, Konstantinos Rorris, Filippos-Paschalis Toulgaridis, Fotios Manousiadis, Konstantinos Xydonas, Sotirios Sideris, Antonios Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title | Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title_full | Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title_fullStr | Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title_full_unstemmed | Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title_short | Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene |
title_sort | chronic thoracic aortic dissection: how to treat, when to intervene |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605429/ https://www.ncbi.nlm.nih.gov/pubmed/36294947 http://dx.doi.org/10.3390/life12101511 |
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