Cargando…

Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study

(1) Background: Pregnant patients with severe forms of coronavirus disease 2019 (COVID-19) can experience adverse pregnancy outcomes. The aim of this study was to retrospectively assess the risk factors associated with admission to the intensive care unit (ICU) of pregnant patients with COVID-19, as...

Descripción completa

Detalles Bibliográficos
Autores principales: Adam, Ana-Maria, Vasilache, Ingrid-Andrada, Socolov, Demetra, Stuparu Cretu, Mariana, Georgescu, Costinela Valerica, Vicoveanu, Petronela, Mihalceanu, Elena, Harabor, Anamaria, Socolov, Razvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605461/
https://www.ncbi.nlm.nih.gov/pubmed/36294376
http://dx.doi.org/10.3390/jcm11206055
_version_ 1784818072522063872
author Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Socolov, Demetra
Stuparu Cretu, Mariana
Georgescu, Costinela Valerica
Vicoveanu, Petronela
Mihalceanu, Elena
Harabor, Anamaria
Socolov, Razvan
author_facet Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Socolov, Demetra
Stuparu Cretu, Mariana
Georgescu, Costinela Valerica
Vicoveanu, Petronela
Mihalceanu, Elena
Harabor, Anamaria
Socolov, Razvan
author_sort Adam, Ana-Maria
collection PubMed
description (1) Background: Pregnant patients with severe forms of coronavirus disease 2019 (COVID-19) can experience adverse pregnancy outcomes. The aim of this study was to retrospectively assess the risk factors associated with admission to the intensive care unit (ICU) of pregnant patients with COVID-19, as well as the pregnancy outcomes of these patients; (2) Methods: Medical records of 31 pregnant patients with COVID-19 admitted to three clinical hospitals from Romania, between October 2020 and November 2021 were examined. The patients were segregated into two groups depending on their clinical evolution: non-ICU admission (n = 19) or ICU admission (n = 12). Clinical and paraclinical findings were evaluated using univariate analysis, and the association of significant risk factors with maternal ICU admission was assessed using a multivariate analysis. Pregnancy outcomes of these patients were also recorded; (3) Results: Pulmonary disease, cough, dyspnea, leukocytosis, thrombocytosis, high serum values of transaminases, serum ferritin, and increased duration of hospital admission were identified as significant risk factors associated with maternal admission to the ICU. No significant differences regarding pregnancy outcomes were noted between the evaluated patients; (4) Conclusions: Specific risk factor identification in pregnant patients with severe forms of COVID-19 could improve the patient’s management.
format Online
Article
Text
id pubmed-9605461
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96054612022-10-27 Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study Adam, Ana-Maria Vasilache, Ingrid-Andrada Socolov, Demetra Stuparu Cretu, Mariana Georgescu, Costinela Valerica Vicoveanu, Petronela Mihalceanu, Elena Harabor, Anamaria Socolov, Razvan J Clin Med Article (1) Background: Pregnant patients with severe forms of coronavirus disease 2019 (COVID-19) can experience adverse pregnancy outcomes. The aim of this study was to retrospectively assess the risk factors associated with admission to the intensive care unit (ICU) of pregnant patients with COVID-19, as well as the pregnancy outcomes of these patients; (2) Methods: Medical records of 31 pregnant patients with COVID-19 admitted to three clinical hospitals from Romania, between October 2020 and November 2021 were examined. The patients were segregated into two groups depending on their clinical evolution: non-ICU admission (n = 19) or ICU admission (n = 12). Clinical and paraclinical findings were evaluated using univariate analysis, and the association of significant risk factors with maternal ICU admission was assessed using a multivariate analysis. Pregnancy outcomes of these patients were also recorded; (3) Results: Pulmonary disease, cough, dyspnea, leukocytosis, thrombocytosis, high serum values of transaminases, serum ferritin, and increased duration of hospital admission were identified as significant risk factors associated with maternal admission to the ICU. No significant differences regarding pregnancy outcomes were noted between the evaluated patients; (4) Conclusions: Specific risk factor identification in pregnant patients with severe forms of COVID-19 could improve the patient’s management. MDPI 2022-10-13 /pmc/articles/PMC9605461/ /pubmed/36294376 http://dx.doi.org/10.3390/jcm11206055 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Socolov, Demetra
Stuparu Cretu, Mariana
Georgescu, Costinela Valerica
Vicoveanu, Petronela
Mihalceanu, Elena
Harabor, Anamaria
Socolov, Razvan
Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title_full Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title_fullStr Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title_full_unstemmed Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title_short Risk Factors Associated with Severe Disease and Intensive Care Unit Admission of Pregnant Patients with COVID-19 Infection—A Retrospective Study
title_sort risk factors associated with severe disease and intensive care unit admission of pregnant patients with covid-19 infection—a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605461/
https://www.ncbi.nlm.nih.gov/pubmed/36294376
http://dx.doi.org/10.3390/jcm11206055
work_keys_str_mv AT adamanamaria riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT vasilacheingridandrada riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT socolovdemetra riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT stuparucretumariana riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT georgescucostinelavalerica riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT vicoveanupetronela riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT mihalceanuelena riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT haraboranamaria riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy
AT socolovrazvan riskfactorsassociatedwithseverediseaseandintensivecareunitadmissionofpregnantpatientswithcovid19infectionaretrospectivestudy