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Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center
The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better than organ-based approaches are believed to serve su...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605534/ https://www.ncbi.nlm.nih.gov/pubmed/36294885 http://dx.doi.org/10.3390/jpm12101746 |
| _version_ | 1784818090989584384 |
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| author | Nero, Camilla Duranti, Simona Giacomini, Flavia Minucci, Angelo Giacò, Luciano Piermattei, Alessia Genuardi, Maurizio Pasciuto, Tina Urbani, Andrea Daniele, Gennaro Lorusso, Domenica Pignataro, Raffaele Tortora, Giampaolo Normanno, Nicola Scambia, Giovanni |
| author_facet | Nero, Camilla Duranti, Simona Giacomini, Flavia Minucci, Angelo Giacò, Luciano Piermattei, Alessia Genuardi, Maurizio Pasciuto, Tina Urbani, Andrea Daniele, Gennaro Lorusso, Domenica Pignataro, Raffaele Tortora, Giampaolo Normanno, Nicola Scambia, Giovanni |
| author_sort | Nero, Camilla |
| collection | PubMed |
| description | The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better than organ-based approaches are believed to serve such dynamic purposes. We here present the workflow our institution adopted to run a comprehensive cancer genome profiling in clinical practice. This article describes the workflow designed to make a comprehensive cancer genome profiling program feasible and sustainable in a large-volume referral hospital. |
| format | Online Article Text |
| id | pubmed-9605534 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-96055342022-10-27 Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center Nero, Camilla Duranti, Simona Giacomini, Flavia Minucci, Angelo Giacò, Luciano Piermattei, Alessia Genuardi, Maurizio Pasciuto, Tina Urbani, Andrea Daniele, Gennaro Lorusso, Domenica Pignataro, Raffaele Tortora, Giampaolo Normanno, Nicola Scambia, Giovanni J Pers Med Commentary The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better than organ-based approaches are believed to serve such dynamic purposes. We here present the workflow our institution adopted to run a comprehensive cancer genome profiling in clinical practice. This article describes the workflow designed to make a comprehensive cancer genome profiling program feasible and sustainable in a large-volume referral hospital. MDPI 2022-10-20 /pmc/articles/PMC9605534/ /pubmed/36294885 http://dx.doi.org/10.3390/jpm12101746 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Commentary Nero, Camilla Duranti, Simona Giacomini, Flavia Minucci, Angelo Giacò, Luciano Piermattei, Alessia Genuardi, Maurizio Pasciuto, Tina Urbani, Andrea Daniele, Gennaro Lorusso, Domenica Pignataro, Raffaele Tortora, Giampaolo Normanno, Nicola Scambia, Giovanni Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title | Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title_full | Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title_fullStr | Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title_full_unstemmed | Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title_short | Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center |
| title_sort | integrating a comprehensive cancer genome profiling into clinical practice: a blueprint in an italian referral center |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605534/ https://www.ncbi.nlm.nih.gov/pubmed/36294885 http://dx.doi.org/10.3390/jpm12101746 |
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