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The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications

BACKGROUND: Type 2 diabetes mellitus (T2DM), especially hyperglycemia, is associated with increased glucose cell toxicity and oxidative stress that can lead to irreversible damage in the kidney such as diabetic nephropathy (DN). Autophagy plays a key role in the degradation of damaged intracellular...

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Detalles Bibliográficos
Autores principales: Saad, Ranin, Tadmor, Hagar, Ertracht, Offir, Nakhoul, Nakhoul, Nakhoul, Farid, Evgeny, Farber, Atar, Shaul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605841/
https://www.ncbi.nlm.nih.gov/pubmed/36313818
http://dx.doi.org/10.1155/2022/8337823