Frequency of Rh and K antigens in blood donors in Riyadh

OBJECTIVES: Investigate the prevalence of Rh and the K antigens and their phenotypes in the red blood cells of blood donors in Riyadh, Saudi Arabia. METHODS: This is a retrospective study. The five principal Rh antigens (D, C, c, E, e) and the Kell antigen from the Kell blood group were tested in 4,...

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Autores principales: Alalshaikh, Mohrah, Almalki, Yasser, Hasanato, Rana, Almomen, Abdulkareem, Alsughayir, Ammar, Alabdullateef, Abdulmajeed, Sabbar, Abdullah, Alsuhaibani, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605887/
https://www.ncbi.nlm.nih.gov/pubmed/33992594
http://dx.doi.org/10.1016/j.htct.2021.03.003
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author Alalshaikh, Mohrah
Almalki, Yasser
Hasanato, Rana
Almomen, Abdulkareem
Alsughayir, Ammar
Alabdullateef, Abdulmajeed
Sabbar, Abdullah
Alsuhaibani, Omar
author_facet Alalshaikh, Mohrah
Almalki, Yasser
Hasanato, Rana
Almomen, Abdulkareem
Alsughayir, Ammar
Alabdullateef, Abdulmajeed
Sabbar, Abdullah
Alsuhaibani, Omar
author_sort Alalshaikh, Mohrah
collection PubMed
description OBJECTIVES: Investigate the prevalence of Rh and the K antigens and their phenotypes in the red blood cells of blood donors in Riyadh, Saudi Arabia. METHODS: This is a retrospective study. The five principal Rh antigens (D, C, c, E, e) and the Kell antigen from the Kell blood group were tested in 4,675 random samples collected from four blood bank centers in Riyadh. Data were collected for seven weeks (from January 4, 2019 to February 28, 2019). Antigens were tested using the TANGO Optimo system. RESULTS: We found that approximately 86% of the donors had the D antigen, 66% had C, 78% had c, 26% had E, 97% had e and 14% had K. The most common Rh phenotypes were R1r (31%) and R1R1 (22%). CONCLUSION: The differences in the results between the study population and other populations, such as Caucasian, Indian and African populations indicate the importance of establishing a population-specific database.
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spelling pubmed-96058872022-10-28 Frequency of Rh and K antigens in blood donors in Riyadh Alalshaikh, Mohrah Almalki, Yasser Hasanato, Rana Almomen, Abdulkareem Alsughayir, Ammar Alabdullateef, Abdulmajeed Sabbar, Abdullah Alsuhaibani, Omar Hematol Transfus Cell Ther Original Article OBJECTIVES: Investigate the prevalence of Rh and the K antigens and their phenotypes in the red blood cells of blood donors in Riyadh, Saudi Arabia. METHODS: This is a retrospective study. The five principal Rh antigens (D, C, c, E, e) and the Kell antigen from the Kell blood group were tested in 4,675 random samples collected from four blood bank centers in Riyadh. Data were collected for seven weeks (from January 4, 2019 to February 28, 2019). Antigens were tested using the TANGO Optimo system. RESULTS: We found that approximately 86% of the donors had the D antigen, 66% had C, 78% had c, 26% had E, 97% had e and 14% had K. The most common Rh phenotypes were R1r (31%) and R1R1 (22%). CONCLUSION: The differences in the results between the study population and other populations, such as Caucasian, Indian and African populations indicate the importance of establishing a population-specific database. Sociedade Brasileira de Hematologia e Hemoterapia 2022 2021-05-02 /pmc/articles/PMC9605887/ /pubmed/33992594 http://dx.doi.org/10.1016/j.htct.2021.03.003 Text en © 2021 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Alalshaikh, Mohrah
Almalki, Yasser
Hasanato, Rana
Almomen, Abdulkareem
Alsughayir, Ammar
Alabdullateef, Abdulmajeed
Sabbar, Abdullah
Alsuhaibani, Omar
Frequency of Rh and K antigens in blood donors in Riyadh
title Frequency of Rh and K antigens in blood donors in Riyadh
title_full Frequency of Rh and K antigens in blood donors in Riyadh
title_fullStr Frequency of Rh and K antigens in blood donors in Riyadh
title_full_unstemmed Frequency of Rh and K antigens in blood donors in Riyadh
title_short Frequency of Rh and K antigens in blood donors in Riyadh
title_sort frequency of rh and k antigens in blood donors in riyadh
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605887/
https://www.ncbi.nlm.nih.gov/pubmed/33992594
http://dx.doi.org/10.1016/j.htct.2021.03.003
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