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Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda

Artemisinin partial resistance may facilitate selection of Plasmodium falciparum resistant to combination therapy partner drugs. We evaluated 99 P. falciparum isolates collected in 2021 from northern Uganda, where resistance-associated PfK13 C469Y and A675V mutations have emerged, and eastern Uganda...

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Detalles Bibliográficos
Autores principales: Tumwebaze, Patrick K., Conrad, Melissa D., Okitwi, Martin, Orena, Stephen, Byaruhanga, Oswald, Katairo, Thomas, Legac, Jennifer, Garg, Shreeya, Giesbrecht, David, Smith, Sawyer R., Ceja, Frida G., Nsobya, Samuel L., Bailey, Jeffrey A., Cooper, Roland A., Rosenthal, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605985/
https://www.ncbi.nlm.nih.gov/pubmed/36289202
http://dx.doi.org/10.1038/s41467-022-33873-x