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Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly

In response to improper kinetochore-microtubule attachments in mitosis, the spindle assembly checkpoint (SAC) assembles the mitotic checkpoint complex (MCC) to inhibit the anaphase-promoting complex/cyclosome, thereby delaying entry into anaphase. The MCC comprises Mad2:Cdc20:BubR1:Bub3. Its assembl...

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Detalles Bibliográficos
Autores principales:	Fischer, Elyse S., Yu, Conny W. H., Hevler, Johannes F., McLaughlin, Stephen H., Maslen, Sarah L., Heck, Albert J. R., Freund, Stefan M. V., Barford, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605988/ https://www.ncbi.nlm.nih.gov/pubmed/36289199 http://dx.doi.org/10.1038/s41467-022-34058-2

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