Do Cancer and Cancer Treatments Accelerate Aging?

PURPOSE OF REVIEW: This review focuses on describing the mechanisms and clinical manifestations that underlie accelerated aging associated with cancer and its treatment. RECENT FINDINGS: The direct and indirect effects of cancer and its treatment are associated with late occurrence of comorbidities...

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Autores principales: Bhatia, Roma, Holtan, Shernan, Jurdi, Najla El, Prizment, Anna, Blaes, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Geriatric Oncology (L Balducci, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606015/
https://www.ncbi.nlm.nih.gov/pubmed/35796942
http://dx.doi.org/10.1007/s11912-022-01311-2
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author Bhatia, Roma
Holtan, Shernan
Jurdi, Najla El
Prizment, Anna
Blaes, Anne
author_facet Bhatia, Roma
Holtan, Shernan
Jurdi, Najla El
Prizment, Anna
Blaes, Anne
author_sort Bhatia, Roma
collection PubMed
description PURPOSE OF REVIEW: This review focuses on describing the mechanisms and clinical manifestations that underlie accelerated aging associated with cancer and its treatment. RECENT FINDINGS: The direct and indirect effects of cancer and its treatment are associated with late occurrence of comorbidities that happen earlier or more frequently in cancer survivors compared to cancer-free individuals, otherwise known as accelerated aging. Use of senolytics and dietary and exercise interventions including prehabilitation, caloric restriction, and rehabilitation are currently under investigation to reverse or decelerate the aging process and will be covered in this review. SUMMARY: Further research on how to decelerate or reverse aging changes associated with cancer and its treatment will be of paramount importance as the number of cancer survivors continues to grow.
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spelling pubmed-96060152022-10-28 Do Cancer and Cancer Treatments Accelerate Aging? Bhatia, Roma Holtan, Shernan Jurdi, Najla El Prizment, Anna Blaes, Anne Curr Oncol Rep Geriatric Oncology (L Balducci, Section Editor) PURPOSE OF REVIEW: This review focuses on describing the mechanisms and clinical manifestations that underlie accelerated aging associated with cancer and its treatment. RECENT FINDINGS: The direct and indirect effects of cancer and its treatment are associated with late occurrence of comorbidities that happen earlier or more frequently in cancer survivors compared to cancer-free individuals, otherwise known as accelerated aging. Use of senolytics and dietary and exercise interventions including prehabilitation, caloric restriction, and rehabilitation are currently under investigation to reverse or decelerate the aging process and will be covered in this review. SUMMARY: Further research on how to decelerate or reverse aging changes associated with cancer and its treatment will be of paramount importance as the number of cancer survivors continues to grow. Springer US 2022-07-07 2022 /pmc/articles/PMC9606015/ /pubmed/35796942 http://dx.doi.org/10.1007/s11912-022-01311-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Geriatric Oncology (L Balducci, Section Editor)
Bhatia, Roma
Holtan, Shernan
Jurdi, Najla El
Prizment, Anna
Blaes, Anne
Do Cancer and Cancer Treatments Accelerate Aging?
title Do Cancer and Cancer Treatments Accelerate Aging?
title_full Do Cancer and Cancer Treatments Accelerate Aging?
title_fullStr Do Cancer and Cancer Treatments Accelerate Aging?
title_full_unstemmed Do Cancer and Cancer Treatments Accelerate Aging?
title_short Do Cancer and Cancer Treatments Accelerate Aging?
title_sort do cancer and cancer treatments accelerate aging?
topic Geriatric Oncology (L Balducci, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606015/
https://www.ncbi.nlm.nih.gov/pubmed/35796942
http://dx.doi.org/10.1007/s11912-022-01311-2
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