Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis

Indoleamine 2,3 dioxygenase-1 (IDO1) catalyzes tryptophan-kynurenine metabolism in many inflammatory and cancer diseases. Of note, acute inflammation that occurs immediately after heart injury is essential for neonatal cardiomyocyte proliferation and heart regeneration. However, the IDO1-catalyzed t...

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Detalles Bibliográficos
Autores principales: Zhang, Donghong, Ning, Jinfeng, Ramprasath, Tharmarajan, Yu, Changjiang, Zheng, Xiaoxu, Song, Ping, Xie, Zhonglin, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606021/
https://www.ncbi.nlm.nih.gov/pubmed/36289221
http://dx.doi.org/10.1038/s41467-022-33734-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606021/
https://www.ncbi.nlm.nih.gov/pubmed/36289221
http://dx.doi.org/10.1038/s41467-022-33734-7

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