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STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells

Inserting large DNA payloads (>10 kb) into specific genomic sites of mammalian cells remains challenging. Applications ranging from synthetic biology to evaluating the pathogenicity of disease-associated variants for precision medicine initiatives would greatly benefit from tools that facilitate...

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Detalles Bibliográficos
Autores principales:	Blanch-Asensio, Albert, Grandela, Catarina, Brandão, Karina O., de Korte, Tessa, Mei, Hailiang, Ariyurek, Yavuz, Yiangou, Loukia, Mol, Mervyn P.H., van Meer, Berend J., Kloet, Susan L., Mummery, Christine L., Davis, Richard P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606106/ https://www.ncbi.nlm.nih.gov/pubmed/36313798 http://dx.doi.org/10.1016/j.crmeth.2022.100300

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