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Distinctive aspects of the placental epigenome and theories as to how they arise
The placenta has a methylome dramatically unlike that of any somatic cell type. Among other distinctions, it features low global DNA methylation, extensive “partially methylated domains” packed in dense heterochromatin and methylation of hundreds of CpG islands important in somatic development. Thes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606139/ https://www.ncbi.nlm.nih.gov/pubmed/36287261 http://dx.doi.org/10.1007/s00018-022-04568-9 |