Synthetic PPAR Agonist DTMB Alleviates Alzheimer’s Disease Pathology by Inhibition of Chronic Microglial Inflammation in 5xFAD Mice

Abnormal productions of amyloid beta (Aβ) plaque and chronic neuroinflammation are commonly observed in the brain of patients with Alzheimer’s disease, and both of which induce neuronal cell death, loss of memory, and cognitive dysfunction. However, many of the drugs targeting the production of Aβ p...

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Detalles Bibliográficos
Autores principales: Oh, Eunji, Kang, Jeong-Hwa, Jo, Kyung Won, Shin, Won-Sik, Jeong, Young-Hun, Kang, Byunghee, Rho, Tae-Young, Jeon, So Yeon, Lee, Jihoon, Song, Im-Sook, Kim, Kyong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606171/
https://www.ncbi.nlm.nih.gov/pubmed/35917087
http://dx.doi.org/10.1007/s13311-022-01275-y

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