P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica: P2R Inhibitors Prevent Autoantibody Injury

Purinergic 2 receptors (P2Rs) contribute to disease-related immune cell signaling and are upregulated in various pathological settings, including neuroinflammation. P2R inhibitors have been used to treat inflammatory diseases and can protect against complement-mediated cell injury. However, the mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Kalluri, Sudhakar Reddy, Srivastava, Rajneesh, Kenet, Selin, Tanti, Goutam K., Dornmair, Klaus, Bennett, Jeffrey L., Misgeld, Thomas, Hemmer, Bernhard, Wyss, Matthias T., Herwerth, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606199/
https://www.ncbi.nlm.nih.gov/pubmed/35821382
http://dx.doi.org/10.1007/s13311-022-01269-w

Ejemplares similares

Ejemplares similares