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Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease
BACKGROUND: This study aimed to define changes in the metabolic and protein profiles of patients with calcific aortic valve disease (CAVD). METHODS AND RESULTS: We analyzed cardiac valve samples of patients with and without (control) CAVD (n = 24 per group) using untargeted metabolomics and tandem m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606238/ https://www.ncbi.nlm.nih.gov/pubmed/36312243 http://dx.doi.org/10.3389/fcvm.2022.944521 |