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The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization

Mitophagy is a vital process that controls mitochondria quality, dysregulation of which can promote cancer. Oncoprotein mucin 1 (MUC1) targets mitochondria to attenuate drug-induced apoptosis. However, little is known about whether and how MUC1 contributes to mitochondrial homeostasis in cancer cell...

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Detalles Bibliográficos
Autores principales: Li, Quanfu, Chu, Yunkai, Li, Shengze, Yu, Liping, Deng, Huayun, Liao, Chunhua, Liao, Xiaodong, Yang, Chihyu, Qi, Min, Cheng, Jinke, Chen, Guoqiang, Huang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606306/
https://www.ncbi.nlm.nih.gov/pubmed/36289190
http://dx.doi.org/10.1038/s41419-022-05345-z