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Age-dependent antibody profiles to plasmodium antigens are differentially associated with two artemisinin combination therapy outcomes in high transmission setting

The impact of pre-existing immunity on the efficacy of artemisinin combination therapy is largely unknown. We performed in-depth profiling of serological responses in a therapeutic efficacy study [comparing artesunate-mefloquine (ASMQ) and artemether-lumefantrine (AL)] using a proteomic microarray....

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Detalles Bibliográficos
Autores principales:	Andagalu, Ben, Lu, Pinyi, Onyango, Irene, Bergmann-Leitner, Elke, Wasuna, Ruth, Odhiambo, Geoffrey, Chebon-Bore, Lorna J., Ingasia, Luicer A., Juma, Dennis W., Opot, Benjamin, Cheruiyot, Agnes, Yeda, Redemptah, Okudo, Charles, Okoth, Raphael, Chemwor, Gladys, Campo, Joseph, Wallqvist, Anders, Akala, Hoseah M., Ochiel, Daniel, Ogutu, Bernhards, Chaudhury, Sidhartha, Kamau, Edwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606348/ https://www.ncbi.nlm.nih.gov/pubmed/36314027 http://dx.doi.org/10.3389/fmed.2022.991807

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