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Small-molecule compound SYG-180-2-2 attenuates Staphylococcus aureus virulence by inhibiting hemolysin and staphyloxanthin production

Multi-drug resistant Staphylococcus aureus infection is still a serious threat to global health. Therefore, there is an urgent need to develop new antibacterial agents based on virulence factor therapy to overcome drug resistance. Previously, we synthesized SYG-180-2-2 (C(21)H(16)N(2)OSe), an effect...

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Detalles Bibliográficos
Autores principales: Rao, Lulin, Xu, Yanlei, Shen, Li, Wang, Xinyi, Zhao, Huilin, Wang, Bingjie, Zhang, Jiao, Xiao, Yanghua, Guo, Yinjuan, Sheng, Yaoguang, Cheng, Lixia, Song, Zengqiang, Yu, Fangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606476/
https://www.ncbi.nlm.nih.gov/pubmed/36310881
http://dx.doi.org/10.3389/fcimb.2022.1008289