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Efficacy and safety of upadacitinib for active ankylosing spondylitis refractory to biological therapy: a double-blind, randomised, placebo-controlled phase 3 trial

OBJECTIVES: To evaluate the efficacy and safety of upadacitinib, a Janus kinase inhibitor, in patients with active ankylosing spondylitis (AS) with an inadequate response (IR) to biological disease-modifying antirheumatic drugs (bDMARDs). METHODS: Adults with active AS who met modified New York crit...

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Detalles Bibliográficos
Autores principales:	van der Heijde, Désirée, Baraliakos, Xenofon, Sieper, Joachim, Deodhar, Atul, Inman, Robert D, Kameda, Hideto, Zeng, Xiaofeng, Sui, Yunxia, Bu, Xianwei, Pangan, Aileen L, Wung, Peter, Song, In-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Spondyloarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606523/ https://www.ncbi.nlm.nih.gov/pubmed/35788492 http://dx.doi.org/10.1136/ard-2022-222608

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