DNA-PKcs restricts Zika virus spreading and is required for effective antiviral response

Zika virus (ZIKV) is a single-strand RNA mosquito-borne flavivirus with significant public health impact. ZIKV infection induces double-strand DNA breaks (DSBs) in human neural progenitor cells that may contribute to severe neuronal manifestations in newborns. The DNA-PK complex plays a critical rol...

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Detalles Bibliográficos
Autores principales: Patricio, Daniel de Oliveira, Dias, Greicy Brisa Malaquias, Granella, Lucilene Wildner, Trigg, Ben, Teague, Helena Claire, Bittencourt, Dina, Báfica, André, Zanotto-Filho, Alfeu, Ferguson, Brian, Mansur, Daniel Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606669/
https://www.ncbi.nlm.nih.gov/pubmed/36311766
http://dx.doi.org/10.3389/fimmu.2022.1042463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606669/
https://www.ncbi.nlm.nih.gov/pubmed/36311766
http://dx.doi.org/10.3389/fimmu.2022.1042463

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