Real-time imaging of RNA polymerase I activity in living human cells

RNA polymerase I (Pol I) synthesizes about 60% of cellular RNA by transcribing multiple copies of the ribosomal RNA gene (rDNA). The transcriptional activity of Pol I controls the level of ribosome biogenesis and cell growth. However, there is currently a lack of methods for monitoring Pol I activit...

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Detalles Bibliográficos
Autores principales: Fu, Yujuan, Liu, Yaxin, Wen, Tanye, Fang, Jie, Chen, Yalong, Zhou, Ziying, Gu, Xinyi, Wu, Hao, Sheng, Jinghao, Xu, Zhengping, Zou, Wei, Chen, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606689/
https://www.ncbi.nlm.nih.gov/pubmed/36282216
http://dx.doi.org/10.1083/jcb.202202110

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