Reagent-Controlled Highly Stereoselective Difluoromethylation: Efficient Access to Chiral α-Difluoromethylamines from Ketimines

A reagent-controlled highly stereoselective reaction between (S)-difluoromethyl phenyl sulfoximine 1 and imines is reported, and this synthetic method provides a variety of enantiomerically enriched α-difluoromethyl amines. The main pros of this approach include high efficiency, high stereoselectivi...

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Detalles Bibliográficos
Autores principales: Liu, Qinghe, Kong, Taige, Ni, Chuanfa, Hu, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606888/
https://www.ncbi.nlm.nih.gov/pubmed/36296670
http://dx.doi.org/10.3390/molecules27207076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606888/
https://www.ncbi.nlm.nih.gov/pubmed/36296670
http://dx.doi.org/10.3390/molecules27207076

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