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Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification

Brain metastases (BMs) happen often in patients with metastatic cancer (MC), requiring initial and precise diagnosis of BMs, which remains important for medical care preparation and radiotherapy prognostication. Nevertheless, the susceptibility of automated BM (ABMS) diagnosis is unfairly great for...

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Autor principal: Alshammari, Abdulaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606896/
https://www.ncbi.nlm.nih.gov/pubmed/36298426
http://dx.doi.org/10.3390/s22208076
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author Alshammari, Abdulaziz
author_facet Alshammari, Abdulaziz
author_sort Alshammari, Abdulaziz
collection PubMed
description Brain metastases (BMs) happen often in patients with metastatic cancer (MC), requiring initial and precise diagnosis of BMs, which remains important for medical care preparation and radiotherapy prognostication. Nevertheless, the susceptibility of automated BM (ABMS) diagnosis is unfairly great for minute BMs, and integrating into medical exercises to distinguish true metastases (MtS) from false positives remains difficult. For enhancing BM classification execution, MtS localization is performed through the NestNet framework. Subsequent to segmentation, classification is performed by employing the VGG16 convolution neural network. A novel loss function is computed by employing the weighted softmax function (WSF) for enhancing minute MtS diagnosis and for calibrating susceptibility and particularity. The aim of this study was to merge temporal prior data for ABMS detection. The proffered VGG16_CNN is capable of differentiating positive MtS among MtS candidates with high confidence, which typically needs distinct specialist analysis or additional investigation, remaining specifically apt for specialist reinforcement in actual medical practice. The proffered VGG16_CNN framework can be correlated with three advanced methodologies (moU-Net, DSNet, and U-Net) concerning diverse criteria. It was observed that the proffered VGG16_CNN attained 93.74% accuracy, 92% precision, 92.1% recall, and 67.08% F1-score.
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spelling pubmed-96068962022-10-28 Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification Alshammari, Abdulaziz Sensors (Basel) Article Brain metastases (BMs) happen often in patients with metastatic cancer (MC), requiring initial and precise diagnosis of BMs, which remains important for medical care preparation and radiotherapy prognostication. Nevertheless, the susceptibility of automated BM (ABMS) diagnosis is unfairly great for minute BMs, and integrating into medical exercises to distinguish true metastases (MtS) from false positives remains difficult. For enhancing BM classification execution, MtS localization is performed through the NestNet framework. Subsequent to segmentation, classification is performed by employing the VGG16 convolution neural network. A novel loss function is computed by employing the weighted softmax function (WSF) for enhancing minute MtS diagnosis and for calibrating susceptibility and particularity. The aim of this study was to merge temporal prior data for ABMS detection. The proffered VGG16_CNN is capable of differentiating positive MtS among MtS candidates with high confidence, which typically needs distinct specialist analysis or additional investigation, remaining specifically apt for specialist reinforcement in actual medical practice. The proffered VGG16_CNN framework can be correlated with three advanced methodologies (moU-Net, DSNet, and U-Net) concerning diverse criteria. It was observed that the proffered VGG16_CNN attained 93.74% accuracy, 92% precision, 92.1% recall, and 67.08% F1-score. MDPI 2022-10-21 /pmc/articles/PMC9606896/ /pubmed/36298426 http://dx.doi.org/10.3390/s22208076 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alshammari, Abdulaziz
Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title_full Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title_fullStr Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title_full_unstemmed Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title_short Construction of VGG16 Convolution Neural Network (VGG16_CNN) Classifier with NestNet-Based Segmentation Paradigm for Brain Metastasis Classification
title_sort construction of vgg16 convolution neural network (vgg16_cnn) classifier with nestnet-based segmentation paradigm for brain metastasis classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606896/
https://www.ncbi.nlm.nih.gov/pubmed/36298426
http://dx.doi.org/10.3390/s22208076
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