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Prediction of Prognosis in Patients with Trauma by Using Machine Learning

Background and Objectives: We developed a machine learning algorithm to analyze trauma-related data and predict the mortality and chronic care needs of patients with trauma. Materials and Methods: We recruited admitted patients with trauma during 2015 and 2016 and collected their clinical data. Then...

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Autores principales: Lee, Kuo-Chang, Hsu, Chien-Chin, Lin, Tzu-Chieh, Chiang, Hsiu-Fen, Horng, Gwo-Jiun, Chen, Kuo-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606956/
https://www.ncbi.nlm.nih.gov/pubmed/36295540
http://dx.doi.org/10.3390/medicina58101379
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author Lee, Kuo-Chang
Hsu, Chien-Chin
Lin, Tzu-Chieh
Chiang, Hsiu-Fen
Horng, Gwo-Jiun
Chen, Kuo-Tai
author_facet Lee, Kuo-Chang
Hsu, Chien-Chin
Lin, Tzu-Chieh
Chiang, Hsiu-Fen
Horng, Gwo-Jiun
Chen, Kuo-Tai
author_sort Lee, Kuo-Chang
collection PubMed
description Background and Objectives: We developed a machine learning algorithm to analyze trauma-related data and predict the mortality and chronic care needs of patients with trauma. Materials and Methods: We recruited admitted patients with trauma during 2015 and 2016 and collected their clinical data. Then, we subjected this database to different machine learning techniques and chose the one with the highest accuracy by using cross-validation. The primary endpoint was mortality, and the secondary endpoint was requirement for chronic care. Results: Data of 5871 patients were collected. We then used the eXtreme Gradient Boosting (xGBT) machine learning model to create two algorithms: a complete model and a short-term model. The complete model exhibited an 86% recall for recovery, 30% for chronic care, 67% for mortality, and 80% for complications; the short-term model fitted for ED displayed an 89% recall for recovery, 25% for chronic care, and 41% for mortality. Conclusions: We developed a machine learning algorithm that displayed good recall for the healthy recovery group but unsatisfactory results for those requiring chronic care or having a risk of mortality. The prediction power of this algorithm may be improved by implementing features such as age group classification, severity selection, and score calibration of trauma-related variables.
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spelling pubmed-96069562022-10-28 Prediction of Prognosis in Patients with Trauma by Using Machine Learning Lee, Kuo-Chang Hsu, Chien-Chin Lin, Tzu-Chieh Chiang, Hsiu-Fen Horng, Gwo-Jiun Chen, Kuo-Tai Medicina (Kaunas) Article Background and Objectives: We developed a machine learning algorithm to analyze trauma-related data and predict the mortality and chronic care needs of patients with trauma. Materials and Methods: We recruited admitted patients with trauma during 2015 and 2016 and collected their clinical data. Then, we subjected this database to different machine learning techniques and chose the one with the highest accuracy by using cross-validation. The primary endpoint was mortality, and the secondary endpoint was requirement for chronic care. Results: Data of 5871 patients were collected. We then used the eXtreme Gradient Boosting (xGBT) machine learning model to create two algorithms: a complete model and a short-term model. The complete model exhibited an 86% recall for recovery, 30% for chronic care, 67% for mortality, and 80% for complications; the short-term model fitted for ED displayed an 89% recall for recovery, 25% for chronic care, and 41% for mortality. Conclusions: We developed a machine learning algorithm that displayed good recall for the healthy recovery group but unsatisfactory results for those requiring chronic care or having a risk of mortality. The prediction power of this algorithm may be improved by implementing features such as age group classification, severity selection, and score calibration of trauma-related variables. MDPI 2022-10-01 /pmc/articles/PMC9606956/ /pubmed/36295540 http://dx.doi.org/10.3390/medicina58101379 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Kuo-Chang
Hsu, Chien-Chin
Lin, Tzu-Chieh
Chiang, Hsiu-Fen
Horng, Gwo-Jiun
Chen, Kuo-Tai
Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title_full Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title_fullStr Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title_full_unstemmed Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title_short Prediction of Prognosis in Patients with Trauma by Using Machine Learning
title_sort prediction of prognosis in patients with trauma by using machine learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9606956/
https://www.ncbi.nlm.nih.gov/pubmed/36295540
http://dx.doi.org/10.3390/medicina58101379
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