Expression of Mutant Glycine Receptors in Xenopus Oocytes Using Canonical and Non-Canonical Amino Acids Reveals Distinct Roles of Conserved Proline Residues

Pentameric ligand-gated ion channels (pLGIC) play important roles in fast neuronal signal transmission. Functional receptors are pentamers, with each subunit having an extracellular domain (ECD), a transmembrane domain (TMD) and an intracellular domain. The binding of the agonist to the ECD induces...

Descripción completa

Detalles Bibliográficos
Autores principales: Lummis, Sarah C. R., Dougherty, Dennis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607081/
https://www.ncbi.nlm.nih.gov/pubmed/36295771
http://dx.doi.org/10.3390/membranes12101012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607081/
https://www.ncbi.nlm.nih.gov/pubmed/36295771
http://dx.doi.org/10.3390/membranes12101012

Ejemplares similares