A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells

The receptor tyrosine kinase orphan receptor 1 (ROR1) is absent in most normal adult tissues but overexpressed in various malignancies and is of importance for tumor cell survival, proliferation, and metastasis. In this study, we evaluated the apoptotic effects of a novel small molecule inhibitor of...

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Detalles Bibliográficos
Autores principales: Ghaderi, Amineh, Zhong, Wen, Okhovat, Mohammad Ali, Aschan, Johanna, Svensson, Ann, Sander, Birgitta, Schultz, Johan, Olin, Thomas, Österborg, Anders, Hojjat-Farsangi, Mohammad, Mellstedt, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607197/
https://www.ncbi.nlm.nih.gov/pubmed/36297673
http://dx.doi.org/10.3390/pharmaceutics14102238

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