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Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study
Previous epidemiological studies have reported an increased risk of anemia in people with allergic disorders. However, previous studies have followed a cross-sectional design. The aim of this study was to investigate the association between the two conditions with a cohort dataset. We used data of 8...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607270/ https://www.ncbi.nlm.nih.gov/pubmed/36297019 http://dx.doi.org/10.3390/nu14204335 |
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author | Yang, Limin Sato, Miori Saito-Abe, Mayako Miyaji, Yumiko Shimada, Mami Sato, Chikako Nishizato, Minaho Kumasaka, Natsuhiko Mezawa, Hidetoshi Yamamoto-Hanada, Kiwako Ohya, Yukihiro |
author_facet | Yang, Limin Sato, Miori Saito-Abe, Mayako Miyaji, Yumiko Shimada, Mami Sato, Chikako Nishizato, Minaho Kumasaka, Natsuhiko Mezawa, Hidetoshi Yamamoto-Hanada, Kiwako Ohya, Yukihiro |
author_sort | Yang, Limin |
collection | PubMed |
description | Previous epidemiological studies have reported an increased risk of anemia in people with allergic disorders. However, previous studies have followed a cross-sectional design. The aim of this study was to investigate the association between the two conditions with a cohort dataset. We used data of 80,943 children in the Japan Environment and Children’s Study, the largest birth cohort in Japan. The association between anemia and allergic disorders was evaluated with a logistic regression model and propensity score analysis. After adjusting for potential confounders, children with asthma (odds ratio [OR], 1.85; 95% confidence interval [CI], 1.32–2.60), atopic dermatitis (OR, 2.18; 95% CI, 1.66–2.85), allergic rhinitis (OR, 1.35; 95% CI, 1.05–1.74), allergic rhinoconjunctivitis (OR, 2.95; 95% CI, 1.91–4.54), and food allergies (OR, 1.92; 95% CI, 1.44–2.56) at 2 years of age predicted high odds of developing anemia in the next year. Any allergy at 2 years of age was associated with an increased risk of anemia at the age of 3 years (OR, 1.80; 95% CI, 1.41–2.29). The findings remained stable in the propensity score analysis. Results suggest that allergic diseases were related to caregiver-reported anemia in children. |
format | Online Article Text |
id | pubmed-9607270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96072702022-10-28 Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study Yang, Limin Sato, Miori Saito-Abe, Mayako Miyaji, Yumiko Shimada, Mami Sato, Chikako Nishizato, Minaho Kumasaka, Natsuhiko Mezawa, Hidetoshi Yamamoto-Hanada, Kiwako Ohya, Yukihiro Nutrients Article Previous epidemiological studies have reported an increased risk of anemia in people with allergic disorders. However, previous studies have followed a cross-sectional design. The aim of this study was to investigate the association between the two conditions with a cohort dataset. We used data of 80,943 children in the Japan Environment and Children’s Study, the largest birth cohort in Japan. The association between anemia and allergic disorders was evaluated with a logistic regression model and propensity score analysis. After adjusting for potential confounders, children with asthma (odds ratio [OR], 1.85; 95% confidence interval [CI], 1.32–2.60), atopic dermatitis (OR, 2.18; 95% CI, 1.66–2.85), allergic rhinitis (OR, 1.35; 95% CI, 1.05–1.74), allergic rhinoconjunctivitis (OR, 2.95; 95% CI, 1.91–4.54), and food allergies (OR, 1.92; 95% CI, 1.44–2.56) at 2 years of age predicted high odds of developing anemia in the next year. Any allergy at 2 years of age was associated with an increased risk of anemia at the age of 3 years (OR, 1.80; 95% CI, 1.41–2.29). The findings remained stable in the propensity score analysis. Results suggest that allergic diseases were related to caregiver-reported anemia in children. MDPI 2022-10-17 /pmc/articles/PMC9607270/ /pubmed/36297019 http://dx.doi.org/10.3390/nu14204335 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yang, Limin Sato, Miori Saito-Abe, Mayako Miyaji, Yumiko Shimada, Mami Sato, Chikako Nishizato, Minaho Kumasaka, Natsuhiko Mezawa, Hidetoshi Yamamoto-Hanada, Kiwako Ohya, Yukihiro Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title | Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title_full | Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title_fullStr | Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title_full_unstemmed | Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title_short | Allergic Disorders and Risk of Anemia in Japanese Children: Findings from the Japan Environment and Children’s Study |
title_sort | allergic disorders and risk of anemia in japanese children: findings from the japan environment and children’s study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9607270/ https://www.ncbi.nlm.nih.gov/pubmed/36297019 http://dx.doi.org/10.3390/nu14204335 |
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